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Sr Director, Medical Affairs (Obesity and Metabolic Programs)

Structure Therapeutics
August 23, 2026
Remote friendly (South San Francisco, CA)
United States
Medical Affairs
Position Summary
- Reporting to the Executive Director, Medical Affairs & Advocacy Engagement, lead development and execution of the Medical Strategy for all metabolic programs.
- Shape scientific engagement and communications, identify evidence gaps, and support lifecycle management and cross-functional alignment across clinical development, regulatory, and commercial readiness.
- Build and sustain relationships with KOLs, investigators, healthcare professionals, and patient communities; serve as a key scientific expert internally and externally.

Job Responsibilities
Medical Strategy
- Develop and execute a comprehensive Medical Strategic Plan (insight generation, data dissemination, medical communications) across all obesity and related metabolic programs.
- Lead publication strategy (abstracts, manuscripts, congress presentations).

Scientific & External Engagement
- Build relationships with KOLs, academic institutions, and healthcare providers.
- Present clinical and scientific data; represent the company at medical/community congresses and advisory boards.
- Lead high-level scientific discussions on disease state and treatment landscape.

Evidence Generation & Insights
- Support Investigator-Initiated Trials (IITs) and real-world evidence studies.
- Gather and synthesize insights from HCP interactions.
- Inform clinical development plans and lifecycle management.

Cross-Functional Collaboration
- Partner with clinical development, clinical operations, market access, and commercial teams.
- Review materials for scientific accuracy and compliance via MLR review.
- Ensure activities comply with regulatory and ethical standards.

Qualifications
- Education: MD, PharmD, or PhD in a relevant scientific field.
- Experience: 10+ years in biotech/pharma; strong metabolic disease background (obesity, type 2 diabetes); prior Medical Director (or equivalent) in Medical Affairs.

Skills
- Deep metabolism expertise; direct experience in obesity, type 2 diabetes, or incretin-based therapies (preferred).
- Protocol design experience in metabolism, especially incretin therapies.
- Strong communication/presentation; leadership and team management; strategic thinking.

Travel Required
- Regional/national coverage; travel ~25%.

Benefits
- Base pay range: $260,000–$360,000; eligible for annual performance incentive bonus, new hire equity, ongoing performance-based equity; medical/dental/vision insurance, 401k match, unlimited PTO, paid holidays (including winter shutdown).

Application Instructions
- Apply via the company’s official career page at BambooHR.