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Senior Scientist- Cancer immunology/immunotherapy

AstraZeneca
September 21, 2026
Full-time
Remote friendly (Cambridge, MA)
Worldwide
Clinical Research and Development
Role: Senior Scientist specializing in cancer immunology and immunotherapy within oncology research, focusing on T cell biology, neoantigen discovery, and vaccine development. Responsibilities include designing and executing mechanistic studies, driving antigen validation, analyzing immune responses, and establishing advanced in vitro assay systems to evaluate immunogenicity. The candidate collaborates across discovery teams, contributes to scientific strategy and publications, and ensures compliance with GLP and safety standards. Requirements: Master's degree or equivalent in Immunology or related fields, with at least 2 years postdoctoral or industry experience; expertise in T cell function, antigen presentation, and cancer vaccine technologies; proficiency in immunological assays (e.g., flow cytometry, ELISA, cytokine profiling) and experience with immunopeptidomics and TCR methodologies. Desirable skills include in vivo tumor models, neoantigen workflows, and bioinformatics. The role supports advancing innovative cancer immunotherapies and vaccines, impacting drug discovery programs. Location and travel specifics are not provided.