Senior Medical Director, Radiopharmaceutical Imaging (RPI)
Bristol Myers Squibb
August 29, 2026
Remote
United States
Medical Affairs
Senior Medical Director, Radiopharmaceutical Imaging (RPI)
Job Responsibilities
- Define and own the diagnostic imaging portfolio strategy and target product profiles for nominated candidates.
- Serve as imaging Clinical Development lead; provide medical/scientific direction and ensure decision-oriented development plans.
- Lead cross-functional/matrix teams and external partners (investigators, academic collaborators, CROs, central readers) to design and execute early- and late-phase imaging studies.
- Accountable for protocol concepts and critical documents (protocols, investigator brochures, SAP inputs, clinical study reports, key regulatory/medical communications); perform medical monitoring and data review.
- Provide medical oversight for trial conduct (eligibility/risk assessments, safety review, medical monitoring strategy, escalation pathways with Drug Safety/Pharmacovigilance).
- Lead imaging program governance, including data review and IDMCs/DMCs as applicable.
- Translate research/translational/nonclinical findings into imaging development opportunities and go/no-go recommendations.
- Drive strategic regulatory engagement as clinical lead for health authority interactions.
- Establish relationships with clinical investigators and KOLs; represent externally as needed.
- Work with CROs and vendors to execute trials.
- Participate in health authority interactions and prepare briefing books/regulatory submissions.
- Partner with Medical Affairs and Commercial on evidence-generation strategy and lifecycle plans.
- Contribute to resource planning, timeline/budget management, risk mitigation/contingency planning, and vendor oversight.
- Leverage AI to improve performance via prioritization and scaled adoption.
- Travel ~30%; evening/weekend work may be required.
Education and Experience
- MD (or equivalent) with 8+ years pharma/biotech and/or relevant academic clinical experience, including oncology diagnostic/radiopharmaceutical imaging development through regulatory submissions.
- Demonstrated leadership in clinical development.
- Experience across early- and late-phase protocol development/execution (start-up, conduct oversight, analysis inputs, reporting).
- Proven experience with investigative sites and external vendors (e.g., CROs, imaging core labs).
Skills and Qualifications
- Patient-focused; passion for radiopharmaceuticals/imaging agents.
- Strategic clinical development leadership; matrix leadership and stakeholder alignment.
- Strong scientific judgment and benefit–risk mindset.
- Executive-level communication; represent program with health authorities.
- Strong understanding of radiopharmaceutical imaging agent development, central reading paradigms, imaging endpoints, multicenter operational considerations.
- Ability to function in highly regulated environment; adhere to guidelines/SOPs.
- Solid understanding of GCP and ICH.
Benefits (as stated)
- Health Coverage: Medical, pharmacy, dental, vision.
- Wellbeing Support; EAP.
- Financial well-being/protection: 401(k), disability, life insurance, etc.
- Paid Time Off: flexible time off (unlimited) for US exempt employees; 160 hours annual paid vacation for certain other groups; 11 national holidays plus additional details.
Compensation (as stated)
- Remote (US): $241,768 - $292,966 (additional incentive opportunities may be available).
Application instructions
- Apply for the role (no specific additional instructions provided in the job text).
Job Responsibilities
- Define and own the diagnostic imaging portfolio strategy and target product profiles for nominated candidates.
- Serve as imaging Clinical Development lead; provide medical/scientific direction and ensure decision-oriented development plans.
- Lead cross-functional/matrix teams and external partners (investigators, academic collaborators, CROs, central readers) to design and execute early- and late-phase imaging studies.
- Accountable for protocol concepts and critical documents (protocols, investigator brochures, SAP inputs, clinical study reports, key regulatory/medical communications); perform medical monitoring and data review.
- Provide medical oversight for trial conduct (eligibility/risk assessments, safety review, medical monitoring strategy, escalation pathways with Drug Safety/Pharmacovigilance).
- Lead imaging program governance, including data review and IDMCs/DMCs as applicable.
- Translate research/translational/nonclinical findings into imaging development opportunities and go/no-go recommendations.
- Drive strategic regulatory engagement as clinical lead for health authority interactions.
- Establish relationships with clinical investigators and KOLs; represent externally as needed.
- Work with CROs and vendors to execute trials.
- Participate in health authority interactions and prepare briefing books/regulatory submissions.
- Partner with Medical Affairs and Commercial on evidence-generation strategy and lifecycle plans.
- Contribute to resource planning, timeline/budget management, risk mitigation/contingency planning, and vendor oversight.
- Leverage AI to improve performance via prioritization and scaled adoption.
- Travel ~30%; evening/weekend work may be required.
Education and Experience
- MD (or equivalent) with 8+ years pharma/biotech and/or relevant academic clinical experience, including oncology diagnostic/radiopharmaceutical imaging development through regulatory submissions.
- Demonstrated leadership in clinical development.
- Experience across early- and late-phase protocol development/execution (start-up, conduct oversight, analysis inputs, reporting).
- Proven experience with investigative sites and external vendors (e.g., CROs, imaging core labs).
Skills and Qualifications
- Patient-focused; passion for radiopharmaceuticals/imaging agents.
- Strategic clinical development leadership; matrix leadership and stakeholder alignment.
- Strong scientific judgment and benefit–risk mindset.
- Executive-level communication; represent program with health authorities.
- Strong understanding of radiopharmaceutical imaging agent development, central reading paradigms, imaging endpoints, multicenter operational considerations.
- Ability to function in highly regulated environment; adhere to guidelines/SOPs.
- Solid understanding of GCP and ICH.
Benefits (as stated)
- Health Coverage: Medical, pharmacy, dental, vision.
- Wellbeing Support; EAP.
- Financial well-being/protection: 401(k), disability, life insurance, etc.
- Paid Time Off: flexible time off (unlimited) for US exempt employees; 160 hours annual paid vacation for certain other groups; 11 national holidays plus additional details.
Compensation (as stated)
- Remote (US): $241,768 - $292,966 (additional incentive opportunities may be available).
Application instructions
- Apply for the role (no specific additional instructions provided in the job text).