Senior Medical Director
Keros Therapeutics
August 22, 2026
Remote friendly (Lexington, MA)
United States
Medical Affairs
Job Summary
Reporting to the Executive Medical Director, the Senior Medical Director will serve as the clinical development leader for one or more pipeline products and represent Clinical Development on project teams from asset identification through commercialization and beyond.
Primary Responsibilities
- Serve as Development Leader and represent Clinical Development on Program and Project Strategy Teams.
- Create/revise the Clinical Development Plan (CDP) for global regulatory approval and market access; develop and execute clinical strategy.
- Lead design of scientifically rigorous clinical protocols aligned with the CDP.
- Provide clinical development leadership for timely, high-quality, scientifically rigorous delivery.
- Lead/support clinical components of key documents (Protocols, Investigator’s Brochures, CSRs, INDs/CTAs, NDAs/MAAs, and regulatory responses).
- Oversee Medical Monitor and/or Medical Director(s) and partner with Safety to evaluate drug safety, including safety monitoring and signal detection.
- Collaborate with biostatistics and Clinical Sciences on data analyses and presentations for safety monitoring, regulatory documents, and internal reviews.
- Lead/participate in interactions with internal decision committees and external stakeholders (regulators, KOLs, data monitoring committees, advisory boards, patient advocacy groups).
- Support periodic Steering Committee(s), as applicable.
- Develop/update key messages (disease state, MOA, target product profile, platform).
- Collaborate with Medical Affairs on scientific communication, publication planning, and congress management.
- Support investigators/KOLs/patient advocacy groups for collaboration, patient recruitment, and commercial planning.
- Present data externally and author/review abstracts, posters, and manuscripts.
Qualifications
- MD (or equivalent); Board Certification in Neurology a plus.
- 5+ years clinical development experience in pharma/biotech.
- Knowledge of clinical trial design, methodology, statistical concepts, protocol development/implementation, global regulatory submissions, and drug development.
- Demonstrated clinical development leadership on cross-functional teams.
- Strong analytical, problem-solving, organizational, and communication skills.
Skills/Requirements
- Travel up to 20% required.
- Hybrid schedule: in office at least 3 days/week required.
Potential Base Pay Range
- $317,000—$369,000 USD
Reporting to the Executive Medical Director, the Senior Medical Director will serve as the clinical development leader for one or more pipeline products and represent Clinical Development on project teams from asset identification through commercialization and beyond.
Primary Responsibilities
- Serve as Development Leader and represent Clinical Development on Program and Project Strategy Teams.
- Create/revise the Clinical Development Plan (CDP) for global regulatory approval and market access; develop and execute clinical strategy.
- Lead design of scientifically rigorous clinical protocols aligned with the CDP.
- Provide clinical development leadership for timely, high-quality, scientifically rigorous delivery.
- Lead/support clinical components of key documents (Protocols, Investigator’s Brochures, CSRs, INDs/CTAs, NDAs/MAAs, and regulatory responses).
- Oversee Medical Monitor and/or Medical Director(s) and partner with Safety to evaluate drug safety, including safety monitoring and signal detection.
- Collaborate with biostatistics and Clinical Sciences on data analyses and presentations for safety monitoring, regulatory documents, and internal reviews.
- Lead/participate in interactions with internal decision committees and external stakeholders (regulators, KOLs, data monitoring committees, advisory boards, patient advocacy groups).
- Support periodic Steering Committee(s), as applicable.
- Develop/update key messages (disease state, MOA, target product profile, platform).
- Collaborate with Medical Affairs on scientific communication, publication planning, and congress management.
- Support investigators/KOLs/patient advocacy groups for collaboration, patient recruitment, and commercial planning.
- Present data externally and author/review abstracts, posters, and manuscripts.
Qualifications
- MD (or equivalent); Board Certification in Neurology a plus.
- 5+ years clinical development experience in pharma/biotech.
- Knowledge of clinical trial design, methodology, statistical concepts, protocol development/implementation, global regulatory submissions, and drug development.
- Demonstrated clinical development leadership on cross-functional teams.
- Strong analytical, problem-solving, organizational, and communication skills.
Skills/Requirements
- Travel up to 20% required.
- Hybrid schedule: in office at least 3 days/week required.
Potential Base Pay Range
- $317,000—$369,000 USD