Senior Medical Director
Maze Therapeutics
June 24, 2026
Remote friendly (South San Francisco, CA)
United States
Medical Affairs
Role: Senior Medical Director (Clinical Sciences)
Responsibilities/Impact:
- Lead design, execution, and analysis of clinical trials for the SLC6A19 program and other early-stage assets.
- Author/review clinical-regulatory documents (protocols & amendments, informed consents, study reports, SAPs).
- Prepare/deliver scientific presentations and other communication materials for internal/external stakeholders.
- Engage scientific thought leaders and patient advocacy groups to inform clinical plans.
- Partner with Clinical Development Ops on investigator/site selection and relationship building.
- Partner with Clinical Development Ops to select and oversee vendors/CROs.
- Develop and integrate clinical timelines and budgets with cross-functional stakeholders.
Qualifications:
- MD with 6+ years of drug development industry experience.
- Board eligibility/certification; clinical experience in internal medicine and/or pediatrics. Nephrology or cardiometabolic disease experience preferred.
- Experience as a clinical study medical monitor.
- Experience preparing/submitting clinical-regulatory documents (scientific publications, study protocols, Investigator Brochures, etc.).
- Experience planning/overseeing early-stage or registration-enabling programs (CRO/site selection; relationships with investigators, site staff, advocacy groups, and third parties).
- Demonstrated clinical trial design/conduct and data analysis/interpretation (particularly Phase 2).
- Experience leading cross-functional study teams.
- Willingness to travel domestically/internationally up to 20%.
Benefits/Compensation (as stated):
- Hybrid schedule; onsite at South San Francisco HQ at least 3 days/week.
- Expected salary range (SF Bay Area): $337,500–$412,500; eligible for annual performance bonus.
- Medical/dental/vision, mental health offerings, equity incentive plan, 401(k) match, and generous holiday/PTO.
Responsibilities/Impact:
- Lead design, execution, and analysis of clinical trials for the SLC6A19 program and other early-stage assets.
- Author/review clinical-regulatory documents (protocols & amendments, informed consents, study reports, SAPs).
- Prepare/deliver scientific presentations and other communication materials for internal/external stakeholders.
- Engage scientific thought leaders and patient advocacy groups to inform clinical plans.
- Partner with Clinical Development Ops on investigator/site selection and relationship building.
- Partner with Clinical Development Ops to select and oversee vendors/CROs.
- Develop and integrate clinical timelines and budgets with cross-functional stakeholders.
Qualifications:
- MD with 6+ years of drug development industry experience.
- Board eligibility/certification; clinical experience in internal medicine and/or pediatrics. Nephrology or cardiometabolic disease experience preferred.
- Experience as a clinical study medical monitor.
- Experience preparing/submitting clinical-regulatory documents (scientific publications, study protocols, Investigator Brochures, etc.).
- Experience planning/overseeing early-stage or registration-enabling programs (CRO/site selection; relationships with investigators, site staff, advocacy groups, and third parties).
- Demonstrated clinical trial design/conduct and data analysis/interpretation (particularly Phase 2).
- Experience leading cross-functional study teams.
- Willingness to travel domestically/internationally up to 20%.
Benefits/Compensation (as stated):
- Hybrid schedule; onsite at South San Francisco HQ at least 3 days/week.
- Expected salary range (SF Bay Area): $337,500–$412,500; eligible for annual performance bonus.
- Medical/dental/vision, mental health offerings, equity incentive plan, 401(k) match, and generous holiday/PTO.