Global Scientific Director - Liver Portfolio
Mirum Pharmaceuticals, Inc.
July 03, 2026
Remote friendly (United States)
United States
Medical Affairs
Position Summary
- Responsible for internal and external scientific and clinical research initiatives under Medical Affairs supporting HDV and PSC/PBC (liver portfolio).
- Develop strategy, tactics, KOL engagement plan, and disease-state awareness for adult hepatology programs.
- Manage compassionate use and expanded access programs for HDV and PSC/PBC.
- Member of R&D providing scientific, clinical, and strategic feedback across cross-functional teams.
Responsibilities
- Collaborate across functions to support clinical trials and scientific affairs research for adult hepatology.
- Support scientific/clinical communications for internal/external stakeholders, including advisory boards for adult liver indications.
- Support patient enrollment using adult hepatology/gastroenterology expertise in partnership with clinical study leads, CTLs, and VP of Clinical Development.
- Identify knowledge gaps and develop mitigation strategies via internal resources and external collaborations.
- Lead/collaborate to execute compassionate use and expanded access programs for Brelovitug and Volixibat.
- Oversee internal/external research (natural history studies, forums, real-world data registries, data mining for publications, and other research efforts).
- Support Safety and Regulatory teams using liver disease expertise.
- Analyze clinical research data and conduct relevant literature research.
- Plan and develop/edit publications and conference materials (abstracts, posters, presentations, manuscripts) and execute the publication plan.
- Work with medical affairs infrastructure.
Qualifications
- MD degree required.
- GI/Hepatology experience strongly preferred.
- 3+ years industry experience; prior HDV, PSC, and/or PBC preferred.
- Experience with scientific publications, congress activities, and research forums.
- Plus: experience with data generation, natural history registries, and/or building real-world registries.
Skills/Abilities (Required/Preferred)
- Experience in clinical development and/or medical affairs and scientific research initiatives.
- Strategic thinker with strong attention to detail.
- Strong collaboration with internal/external partners and authors/reviewers.
- Excellent oral/written communication; ability to present complex scientific concepts clearly.
- Ability to write scientific content, research literature, form opinions, and align strategy with stakeholders.
- Plus: rare disease, liver, or gastroenterology experience.
- Responsible for internal and external scientific and clinical research initiatives under Medical Affairs supporting HDV and PSC/PBC (liver portfolio).
- Develop strategy, tactics, KOL engagement plan, and disease-state awareness for adult hepatology programs.
- Manage compassionate use and expanded access programs for HDV and PSC/PBC.
- Member of R&D providing scientific, clinical, and strategic feedback across cross-functional teams.
Responsibilities
- Collaborate across functions to support clinical trials and scientific affairs research for adult hepatology.
- Support scientific/clinical communications for internal/external stakeholders, including advisory boards for adult liver indications.
- Support patient enrollment using adult hepatology/gastroenterology expertise in partnership with clinical study leads, CTLs, and VP of Clinical Development.
- Identify knowledge gaps and develop mitigation strategies via internal resources and external collaborations.
- Lead/collaborate to execute compassionate use and expanded access programs for Brelovitug and Volixibat.
- Oversee internal/external research (natural history studies, forums, real-world data registries, data mining for publications, and other research efforts).
- Support Safety and Regulatory teams using liver disease expertise.
- Analyze clinical research data and conduct relevant literature research.
- Plan and develop/edit publications and conference materials (abstracts, posters, presentations, manuscripts) and execute the publication plan.
- Work with medical affairs infrastructure.
Qualifications
- MD degree required.
- GI/Hepatology experience strongly preferred.
- 3+ years industry experience; prior HDV, PSC, and/or PBC preferred.
- Experience with scientific publications, congress activities, and research forums.
- Plus: experience with data generation, natural history registries, and/or building real-world registries.
Skills/Abilities (Required/Preferred)
- Experience in clinical development and/or medical affairs and scientific research initiatives.
- Strategic thinker with strong attention to detail.
- Strong collaboration with internal/external partners and authors/reviewers.
- Excellent oral/written communication; ability to present complex scientific concepts clearly.
- Ability to write scientific content, research literature, form opinions, and align strategy with stakeholders.
- Plus: rare disease, liver, or gastroenterology experience.