Senior Medical Director
Mineralys Therapeutics, Inc.
June 26, 2026
Remote
United States
Medical Affairs
Position Summary
The Senior Medical Director will shape and execute the global medical affairs strategy in support of the company’s pipeline and future commercial products. This role bridges Clinical Development and Commercial to ensure scientific integrity, evidence generation, and external engagement with key stakeholders. Oversees Health Economics and Outcomes Research (HEOR) and Strategic Alliances & External Engagement, and supports regulatory milestones and commercialization.
Key Responsibilities
Medical Strategy & Leadership
- Develop and lead the global Medical Affairs strategy aligned with clinical development plans and commercial objectives
- Serve as a key medical voice in cross-functional leadership discussions (Clinical, Regulatory, Commercial, Market Access)
- Translate clinical/scientific data into medical strategies supporting differentiation and value demonstration
Scientific Engagement & External Leadership
- Build and maintain relationships with KOLs, academic institutions, and clinical investigators
- Represent the company at scientific congresses, advisory boards, and external forums
- Lead and support advisory board strategy and execution
- Oversee HEOR (RWE, outcomes research, value-based evidence generation)
- Develop and oversee global strategy for sponsorships, grants, and charitable contributions aligned with medical/scientific priorities
- Lead team in identifying/building relationships with key patient organizations
- Provide scientific insights for economic models, burden-of-disease studies, and comparative effectiveness research
Cross-Functional Collaboration
- Partner with Clinical Development on trial design, investigator engagement, and data interpretation
- Collaborate with Commercial and Market Access to ensure scientific alignment and launch readiness support
- Contribute to regulatory strategy/interactions as needed
Launch Readiness
- Lead preparation for first product launch (scientific platform development and field medical readiness)
- Ensure generation and communication of data supporting product value proposition
Qualifications
- MD or DO required
- Cardiovascular experience preferred
- 8+ years in pharma/biotech, including significant Medical Affairs leadership
- Demonstrated HEOR/RWE strategy and execution experience
- Experience supporting late-stage development and/or product launches
- Proven ability to lead cross-functional initiatives and influence senior stakeholders
- Strong external presence with experience engaging KOLs and representing the company at scientific forums
Travel
- Up to 30% travel; frequently outside local area and overnight
Benefits
- Standard Company benefits including medical, dental, vision, time off, and 401K; participation in Mineralys incentive plans contingent on personal and company performance
US Salary Range
- $330,000-$364,000
The Senior Medical Director will shape and execute the global medical affairs strategy in support of the company’s pipeline and future commercial products. This role bridges Clinical Development and Commercial to ensure scientific integrity, evidence generation, and external engagement with key stakeholders. Oversees Health Economics and Outcomes Research (HEOR) and Strategic Alliances & External Engagement, and supports regulatory milestones and commercialization.
Key Responsibilities
Medical Strategy & Leadership
- Develop and lead the global Medical Affairs strategy aligned with clinical development plans and commercial objectives
- Serve as a key medical voice in cross-functional leadership discussions (Clinical, Regulatory, Commercial, Market Access)
- Translate clinical/scientific data into medical strategies supporting differentiation and value demonstration
Scientific Engagement & External Leadership
- Build and maintain relationships with KOLs, academic institutions, and clinical investigators
- Represent the company at scientific congresses, advisory boards, and external forums
- Lead and support advisory board strategy and execution
- Oversee HEOR (RWE, outcomes research, value-based evidence generation)
- Develop and oversee global strategy for sponsorships, grants, and charitable contributions aligned with medical/scientific priorities
- Lead team in identifying/building relationships with key patient organizations
- Provide scientific insights for economic models, burden-of-disease studies, and comparative effectiveness research
Cross-Functional Collaboration
- Partner with Clinical Development on trial design, investigator engagement, and data interpretation
- Collaborate with Commercial and Market Access to ensure scientific alignment and launch readiness support
- Contribute to regulatory strategy/interactions as needed
Launch Readiness
- Lead preparation for first product launch (scientific platform development and field medical readiness)
- Ensure generation and communication of data supporting product value proposition
Qualifications
- MD or DO required
- Cardiovascular experience preferred
- 8+ years in pharma/biotech, including significant Medical Affairs leadership
- Demonstrated HEOR/RWE strategy and execution experience
- Experience supporting late-stage development and/or product launches
- Proven ability to lead cross-functional initiatives and influence senior stakeholders
- Strong external presence with experience engaging KOLs and representing the company at scientific forums
Travel
- Up to 30% travel; frequently outside local area and overnight
Benefits
- Standard Company benefits including medical, dental, vision, time off, and 401K; participation in Mineralys incentive plans contingent on personal and company performance
US Salary Range
- $330,000-$364,000