Senior Medical Director, AATD

Position Overview
- Serve as the foremost internal medical expert for Alpha-1 Antitrypsin Deficiency (AATD).
- Develop, own, and execute the US AATD medical strategy; align with global medical affairs objectives.
- Provide scientific/clinical leadership across AATD product lifecycle (late-stage development through commercialization).
- Lead medical input into strategic planning (evidence generation, data gap analyses, post hoc analyses, long-range planning).
- Mentor and provide day-to-day guidance to the Field Science Director for AATD; ensure field medical activities align to strategy.
- Translate AATD biology and clinical data into actionable medical insights.
Clinical Development & Safety
- Provide AATD-specific medical insights for current/future clinical trials.
- Review medical input on clinical protocols, study designs, and relevant regulatory submissions.
- Support post-marketing surveillance and real-world evidence generation.
- Contribute to risk management and pharmacovigilance (AATD context).
KOL & Communications
- Build strategic relationships with AATD experts/pulmonologists and key opinion leaders.
- Plan advisory boards, expert panels, and AATD scientific meetings; facilitate external collaboration.
- Oversee AATD medical information responses; develop/review AATD medical education and scientific content.
- Support manuscripts/abstracts/presentations; ensure compliance with regulatory and company policies.
Required Qualifications
- MD board certified pulmonologist (or consider PhD/PharmD with strong pulmonary training + industry experience).
- 5+ years US medical affairs experience in pharma/biotech (respiratory space; US-launch experience preferred).
- Clinical/research experience in pulmonology; strong knowledge of pulmonary disease, lung function, and respiratory clinical management relevant to AATD.
- Knowledge of drug development and medical affairs; launch strategy experience.
- Publication/presentation experience in peer-reviewed journals and conferences.
Preferred Qualifications
- Direct clinical experience with AATD or other rare respiratory diseases.
- End-stage development (e.g., Phase III) and regulatory submissions experience.
- Medical affairs leadership (mentoring/managing field personnel); rare disease/specialty area experience beyond pulmonology.
- Familiarity with structuring medical/scientific content for LLM processing.
Benefits (if offered)
- Health and wellbeing benefits, prevention/wellness programs, and at least 14 weeks’ gender-neutral parental leave.