Senior Manager, US Medical Affairs
Dyne Therapeutics
August 13, 2026
Remote friendly (Waltham, MA)
United States
Medical Affairs
Role Summary
The Senior Manager, US Medical Affairs supports execution of Dyne’s US Medical Affairs strategy for the Duchenne Muscular Dystrophy (DMD) program, contributing to launch readiness and planning/delivery of US medical initiatives.
Primary Responsibilities
- Support execution of US Medical Affairs tactical plans for the DMD program.
- Assist with implementing scientific platform materials, congress planning, and medical education initiatives.
- Contribute to cross-functional launch readiness activities aligned to program milestones.
- Support development/deployment of DMD-focused scientific materials, disease state education resources, and field medical tools.
- Partner with the US MSL team for KOL identification, engagement planning, insight gathering, and field metric tracking.
- Translate field insights into actionable recommendations.
- Track and monitor field activity and engagement effectiveness.
- Contribute to development of scientific materials, field tools, and educational content.
- Provide medical review for promotional materials via the Promotional Review Committee (PRC).
- Maintain current scientific knowledge in DMD and Dyne’s therapeutic platform.
- Support planning/execution of medical congresses aligned to DMD milestones.
- Coordinate logistics and execution of US advisory boards and expert engagements.
- Partner with Patient Advocacy, Market Access, and Commercial to support aligned medical activities.
- Ensure activities comply with US regulatory, legal, and compliance standards.
Education and Skills Requirements
- Advanced scientific/clinical degree required (PhD, PharmD, MD, or equivalent).
- 7+ years relevant Medical Affairs experience in pharmaceutical/biotechnology.
- Rare disease experience preferred; neuromuscular disease experience a plus.
- Experience supporting US-based medical tactics, congress activities, or field medical programs.
- Strong scientific acumen; ability to translate clinical data.
- Excellent written and verbal communication skills.
- Ability to work in a fast-paced environment with competing priorities.
- Demonstrated ability to build collaborative relationships.
- Travel up to 25% (occasional overnight and weekend).
- Positive team orientation; aligned to core values.
- Passion for improving the lives of patients with neuromuscular diseases.
Pay Range
$165,000 - $190,000 USD.
The Senior Manager, US Medical Affairs supports execution of Dyne’s US Medical Affairs strategy for the Duchenne Muscular Dystrophy (DMD) program, contributing to launch readiness and planning/delivery of US medical initiatives.
Primary Responsibilities
- Support execution of US Medical Affairs tactical plans for the DMD program.
- Assist with implementing scientific platform materials, congress planning, and medical education initiatives.
- Contribute to cross-functional launch readiness activities aligned to program milestones.
- Support development/deployment of DMD-focused scientific materials, disease state education resources, and field medical tools.
- Partner with the US MSL team for KOL identification, engagement planning, insight gathering, and field metric tracking.
- Translate field insights into actionable recommendations.
- Track and monitor field activity and engagement effectiveness.
- Contribute to development of scientific materials, field tools, and educational content.
- Provide medical review for promotional materials via the Promotional Review Committee (PRC).
- Maintain current scientific knowledge in DMD and Dyne’s therapeutic platform.
- Support planning/execution of medical congresses aligned to DMD milestones.
- Coordinate logistics and execution of US advisory boards and expert engagements.
- Partner with Patient Advocacy, Market Access, and Commercial to support aligned medical activities.
- Ensure activities comply with US regulatory, legal, and compliance standards.
Education and Skills Requirements
- Advanced scientific/clinical degree required (PhD, PharmD, MD, or equivalent).
- 7+ years relevant Medical Affairs experience in pharmaceutical/biotechnology.
- Rare disease experience preferred; neuromuscular disease experience a plus.
- Experience supporting US-based medical tactics, congress activities, or field medical programs.
- Strong scientific acumen; ability to translate clinical data.
- Excellent written and verbal communication skills.
- Ability to work in a fast-paced environment with competing priorities.
- Demonstrated ability to build collaborative relationships.
- Travel up to 25% (occasional overnight and weekend).
- Positive team orientation; aligned to core values.
- Passion for improving the lives of patients with neuromuscular diseases.
Pay Range
$165,000 - $190,000 USD.