Senior Director, Medical Affairs
MBX Biosciences, Inc.
August 19, 2026
Remote friendly (Burlington, MA)
United States
Medical Affairs
Position Summary
The Senior Director, Medical Affairs (Strategy) will lead the development and execution of the Medical Affairs strategy across the portfolio, with an initial focus on canvuparatide toward commercialization. Provide strategic and operational leadership across scientific communications, evidence generation, publication planning, medical education, and KOL engagement to ensure medical excellence through launch preparation and beyond.
Key Responsibilities
- Lead development and execution of overall Medical Affairs strategy and integrated plans across the portfolio (primary focus on canvuparatide during peri launch/launch).
- Develop and maintain the Scientific Communication Platform (SCP) for consistent, evidence-based, compliant messaging.
- Own forward-looking publication and congress strategy aligned to milestones and business objectives.
- Design and implement integrated evidence generation strategy, including LCM planning with Clinical Development and Commercial.
- Build and sustain a strategic KOL engagement plan with KOL mapping and segmentation.
- Plan, lead, and execute scientific advisory boards.
- Develop/review/lifecycle-manage Medical Affairs materials (e.g., core scientific slide decks, Medical Information standard response letters, foundational content for future MSL activities).
- Support clinical trials and scientific programs (investigator engagement, medical education).
- Design and execute scientific communication programs (disease awareness and education).
- Collaborate with Clinical Development, ADT, and Commercial to embed medical insights into cross-functional strategy.
- Support earlier-stage programs with tailored Medical Affairs activities (publications, selective KOL, targeted advisory boards).
- Contribute to evolution and scaling of the Medical Affairs function.
Education & Qualifications
- Advanced scientific degree (MD, PhD, PharmD, or equivalent).
- 5+ years’ experience in Medical Affairs or related field (multi-TA exposure preferred).
- Experience with medical insights processes; synthesizing complex information.
- Proven track record in scientific communications, congress activities, and MLR review.
- Experience in rare diseases or metabolic/endocrine conditions.
- Strong organizational/project management skills; able to lead multiple initiatives in a dynamic pre-launch environment.
- Excellent communication, scientific writing, and stakeholder-management skills.
Travel
- Periodic business travel, including attendance at Together Weeks, Together Days, and functional meetings as requested.
The Senior Director, Medical Affairs (Strategy) will lead the development and execution of the Medical Affairs strategy across the portfolio, with an initial focus on canvuparatide toward commercialization. Provide strategic and operational leadership across scientific communications, evidence generation, publication planning, medical education, and KOL engagement to ensure medical excellence through launch preparation and beyond.
Key Responsibilities
- Lead development and execution of overall Medical Affairs strategy and integrated plans across the portfolio (primary focus on canvuparatide during peri launch/launch).
- Develop and maintain the Scientific Communication Platform (SCP) for consistent, evidence-based, compliant messaging.
- Own forward-looking publication and congress strategy aligned to milestones and business objectives.
- Design and implement integrated evidence generation strategy, including LCM planning with Clinical Development and Commercial.
- Build and sustain a strategic KOL engagement plan with KOL mapping and segmentation.
- Plan, lead, and execute scientific advisory boards.
- Develop/review/lifecycle-manage Medical Affairs materials (e.g., core scientific slide decks, Medical Information standard response letters, foundational content for future MSL activities).
- Support clinical trials and scientific programs (investigator engagement, medical education).
- Design and execute scientific communication programs (disease awareness and education).
- Collaborate with Clinical Development, ADT, and Commercial to embed medical insights into cross-functional strategy.
- Support earlier-stage programs with tailored Medical Affairs activities (publications, selective KOL, targeted advisory boards).
- Contribute to evolution and scaling of the Medical Affairs function.
Education & Qualifications
- Advanced scientific degree (MD, PhD, PharmD, or equivalent).
- 5+ years’ experience in Medical Affairs or related field (multi-TA exposure preferred).
- Experience with medical insights processes; synthesizing complex information.
- Proven track record in scientific communications, congress activities, and MLR review.
- Experience in rare diseases or metabolic/endocrine conditions.
- Strong organizational/project management skills; able to lead multiple initiatives in a dynamic pre-launch environment.
- Excellent communication, scientific writing, and stakeholder-management skills.
Travel
- Periodic business travel, including attendance at Together Weeks, Together Days, and functional meetings as requested.