Senior Director, Global Medical Affairs - Nephrology
Vertex Pharmaceuticals
August 08, 2026
Remote friendly (Boston, MA)
United States
Medical Affairs
General Summary:
The Medical Affairs Senior Director provides medical and scientific leadership in the assigned Therapeutic Area(s) (TA). Works with cross-functional teams to align scientific and medical strategies with corporate and key stakeholder needs, and ensures execution of Nephrology medical plans.
Key Duties And Responsibilities:
- Lead Kidney programs in Medical Affairs; support kidney indications for pove (e.g., IgAN, AMKD and future indications) by interpreting scientific data and assessing impact on understanding of assigned products.
- Develop medical affairs plans, including Launch and Life Cycle Management plans.
- Share country/regional insights with global teams to reflect regional needs in global medical strategies.
- Provide fair and balanced medical information and education to healthcare professionals and payers to support safe and effective use of Vertex drugs.
- Support patient access by aiding preparation/review of reimbursement dossiers and presenting scientific data to access stakeholders.
- Perform/oversee medical/scientific training for field medical teams, commercial, and other internal stakeholders.
- Contribute to the local Brand Team as TA scientific/medical expert; ensure patient well-being and data integrity.
- Ensure country-level compliance with company policies, medical affairs SOPs, GCP and ICH.
- Assess local promotional materials and ensure claims are scientifically supported and presented accurately, fairly, and balanced.
Knowledge And Skills:
- Deep understanding of global medical, regulatory, and commercial (including payer) environments.
- Knowledge of government/industry guidelines for scientific/medical exchange with external stakeholders (e.g., providers, payers, advocacy bodies).
- Deep understanding of market access in key countries.
- Experience writing/reviewing scientific communications.
- Strong written/oral communication skills; ability to influence.
- Relationship-building in a matrixed environment; conflict resolution.
- Track record of planning and delivering high-quality projects on time.
- Ability to work in multidisciplinary, multicultural teams.
Education And Experience:
- M.D. (or equivalent), PhD, or PharmD.
- Typically 11 years of experience or equivalent education/experience.
The Medical Affairs Senior Director provides medical and scientific leadership in the assigned Therapeutic Area(s) (TA). Works with cross-functional teams to align scientific and medical strategies with corporate and key stakeholder needs, and ensures execution of Nephrology medical plans.
Key Duties And Responsibilities:
- Lead Kidney programs in Medical Affairs; support kidney indications for pove (e.g., IgAN, AMKD and future indications) by interpreting scientific data and assessing impact on understanding of assigned products.
- Develop medical affairs plans, including Launch and Life Cycle Management plans.
- Share country/regional insights with global teams to reflect regional needs in global medical strategies.
- Provide fair and balanced medical information and education to healthcare professionals and payers to support safe and effective use of Vertex drugs.
- Support patient access by aiding preparation/review of reimbursement dossiers and presenting scientific data to access stakeholders.
- Perform/oversee medical/scientific training for field medical teams, commercial, and other internal stakeholders.
- Contribute to the local Brand Team as TA scientific/medical expert; ensure patient well-being and data integrity.
- Ensure country-level compliance with company policies, medical affairs SOPs, GCP and ICH.
- Assess local promotional materials and ensure claims are scientifically supported and presented accurately, fairly, and balanced.
Knowledge And Skills:
- Deep understanding of global medical, regulatory, and commercial (including payer) environments.
- Knowledge of government/industry guidelines for scientific/medical exchange with external stakeholders (e.g., providers, payers, advocacy bodies).
- Deep understanding of market access in key countries.
- Experience writing/reviewing scientific communications.
- Strong written/oral communication skills; ability to influence.
- Relationship-building in a matrixed environment; conflict resolution.
- Track record of planning and delivering high-quality projects on time.
- Ability to work in multidisciplinary, multicultural teams.
Education And Experience:
- M.D. (or equivalent), PhD, or PharmD.
- Typically 11 years of experience or equivalent education/experience.