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Senior Director, Global Develoment Financial Planning & Analysis

Vertex Pharmaceuticals
Full-time
Remote friendly (Boston, MA)
United States
$212,000 - $318,000 USD yearly
Corporate Functions

Role Summary

The Senior Director, Global Development FP&A is a seasoned finance leader who partners directly with our Global Clinical Development (early- and late-stage programs) organizations and cross-functional program teams to run global financial planning, forecasting, and strategic analysis. Reporting to the VP of R&D Finance, this highly visible role serves as a strategic advisor to the Chief Medical Officerโ€™s organization and senior leadership, influencing portfolio prioritization and investment decisions through financial insights. The ideal candidate brings deep expertise in clinical trial finance, executive presence, and a proven ability to drive business outcomes in a dynamic, science-driven environment.

Responsibilities

  • Build, maintain, and own clinical program-level budgets (Phase 1 to Phase 3), clinical trial cost models, and forecasts; produce cost-to-complete and cost per patient analysis used in strategic decisions.
  • Lead advanced scenario modeling for clinical programs, including sensitivity analyses on timelines, enrollment rates, and regulatory milestones to inform go/no-go decisions.
  • Translate clinical development plans into financial implications and ROI-based recommendations.
  • Participate in cross-functional program teams and governance committees, providing real-time financial guidance.
  • Deliver program dashboards, KPIs and trend analyses for executive and portfolio reviews.
  • Prepare and present executive-level updates.
  • Lead and develop a team of 6-8 clinical finance professionals: set team priorities, establish processes, and build scalable operating mechanisms for financial support.
  • Drive automation and digital transformation of clinical finance processes, leveraging tools like Hyperion, Oracle, and emerging analytics platforms to improve accuracy and scalability.
  • Mentor staff on forecast accuracy, stakeholder management and financial modeling best practices.
  • Drive a collaborative, service-oriented culture between finance and Global Clinical Development organizations.
  • Oversee month-end and quarter-end close activities related to clinical expense (accruals, reconciliations, GL review).
  • Ensure accurate, timely accruals for CROs, FSPs, sites, labs and other clinical vendors. Maintain audit-ready documentation for clinical program spend.
  • Improve transparency and accountability around clinical opex and resource allocation through clear processes, benchmarks and metrics.

Qualifications

  • Required: Bachelorโ€™s degree in finance, Accounting, or related field; MBA or CPA/CFA strongly preferred.
  • Required: 12+ years of progressive FP&A experience, with at least 5 years in the pharmaceutical or biotech industry.
  • Required: Experience supporting R&D or Clinical Development functions at a global scale.
  • Required: Strong understanding of R&D processes, portfolio management, and project evaluation methodologies.
  • Required: Proven ability to manage complex budgets, forecasts, and analyses in a dynamic, fast-paced environment.
  • Required: Excellent communication and presentation skills, with the ability to influence stakeholders at all levels and present complex financial insights to senior leadership.

Skills

  • Deep understanding of pharmaceutical industry dynamics and executive-level business partnering.
  • Hands-on exposure to clinical operations and/or CRO/FSP budgeting.
  • Strong analytical capabilities in portfolio analysis.
  • Proficiency in Microsoft Office and financial systems, including Hyperion and Oracle.
  • Proven ability to lead change in complex, cross-cultural matrix environments.
  • Exceptional communication and influencing skills across senior leadership and cross-functional teams.
  • Ability to apply broad market knowledge to drive financial performance and strategic outcomes.
  • Strategic thinker with attention to detail.
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