Senior Director, Advanced Pharmacometrics, Quantitative Pharmacology and Pharmacometrics – Immuno-Oncology (Hybrid or Remote)

Role: Senior Director leading advanced pharmacometrics within the Quantitative Pharmacology and Pharmacometrics – Immuno-Oncology (QP2-IO) team, focusing on oncology drug development from candidate nomination through registration. Responsibilities: develop and execute MIDD strategies, oversee modeling of PK/PD, tumor dynamics, survival, and Bayesian approaches; collaborate with clinical, translational, biostatistics, and regulatory teams; ensure regulatory-grade deliverables; foster innovation in modeling methodologies, including AI/ML; lead and mentor a team of quantitative scientists; contribute to external scientific engagements and regulatory submissions. Requirements: Ph.D. in pharmacometrics, pharmacology, mathematics, statistics, or related field with 10+ years (Ph.D.) or 15+ years (Master’s/PharmD) of pharma experience; deep expertise in oncology drug development, population PK/PD, tumor modeling, Bayesian inference, and software like NONMEM, Stan, R; strong leadership, cross-functional influencing, and communication skills. High-value: Oncology, immuno-oncology assets, advanced modeling including Bayesian hierarchical methods, model-informed drug development, regulatory submissions, and external scientific representation. Work setup: remote or hybrid based on location, with approximately 10% travel.