Medical Director, US Medical Affairs, HCM
Cytokinetics
August 21, 2026
Remote friendly (San Francisco Bay Area)
United States
Medical Affairs
Responsibilities:
- Assist in development and execution of medical strategy, including the US Plan of Action, aligned with organizational/therapeutic area/product objectives.
- Serve as medical/scientific expert for hypertrophic cardiomyopathy; educate HCPs on aficamten clinical profile and role in HCM therapy.
- Provide medical leadership through aficamten development, launch readiness, and lifecycle management; execute medical launch activities.
- Provide medical input into cross-functional plans (brand, evidence generation, market access, lifecycle management) and REMS activities.
- Partner with Clinical Development, Commercial, Regulatory, Safety, HEOR, Market Access, and Legal/Compliance on key deliverables (e.g., congress strategy, advisory boards, field force training, medical information standard response letters, health economics/epidemiology analyses, marketing/policy projects).
- Collaborate with global/regional colleagues to align strategy and address local needs; participate in cross-functional Medical/Commercial teams.
- Review HCM/aficamten medical education, grants, and sponsorship; evaluate reach/quality/impact.
- Manage medical programs, vendors, timelines, budgets, contracts, and performance measures.
- Support HCP inquiry responses; review medical/promotional scientific materials via MLR.
- Contribute to integrated evidence plan strategy (IEP), evidence gap identification, real-world evidence, and investigator-sponsored research.
- Establish field medical scientific priorities/training/engagement; analyze field insights; support field materials and education for emerging aficamten/HCM data.
- Build a US KOL HCM expert network and engage external experts for scientific exchange.
Qualifications:
- MD/DO or PharmD with 3–5 years Medical Affairs Medical Director experience (required). Cardiovascular training/clinical experience strongly preferred.
- Strong knowledge of Medical Affairs strategy (evidence generation, scientific communications, external engagement) and strong project management.
- Highly desirable: product approvals/launch/peri-launch experience.
- Preferred/desired: academic medicine/clinical research; familiarity with biostatistics/epidemiology; experience with vendor/budget/timeline management; medical plan development aligning objectives to product/org strategy.
- Familiarity with OPDP, PhRMA code, and key pharma regulations (plus).
- Ability to critically evaluate clinical trial data, literature, guidelines, and RWE; translate complex science into actionable guidance.
- Working knowledge of congress strategy, advisory boards, medical education, scientific communications; strong oral/written communication.
- Proficiency with Microsoft Office; travel ~30%.
Benefits (explicitly stated): equity (stock options/RSUs); comprehensive health/dental/vision/life/disability; 401k match; learning and wellness stipends; paid time off.
Application instructions: Review GDPR policy prior to applying.
- Assist in development and execution of medical strategy, including the US Plan of Action, aligned with organizational/therapeutic area/product objectives.
- Serve as medical/scientific expert for hypertrophic cardiomyopathy; educate HCPs on aficamten clinical profile and role in HCM therapy.
- Provide medical leadership through aficamten development, launch readiness, and lifecycle management; execute medical launch activities.
- Provide medical input into cross-functional plans (brand, evidence generation, market access, lifecycle management) and REMS activities.
- Partner with Clinical Development, Commercial, Regulatory, Safety, HEOR, Market Access, and Legal/Compliance on key deliverables (e.g., congress strategy, advisory boards, field force training, medical information standard response letters, health economics/epidemiology analyses, marketing/policy projects).
- Collaborate with global/regional colleagues to align strategy and address local needs; participate in cross-functional Medical/Commercial teams.
- Review HCM/aficamten medical education, grants, and sponsorship; evaluate reach/quality/impact.
- Manage medical programs, vendors, timelines, budgets, contracts, and performance measures.
- Support HCP inquiry responses; review medical/promotional scientific materials via MLR.
- Contribute to integrated evidence plan strategy (IEP), evidence gap identification, real-world evidence, and investigator-sponsored research.
- Establish field medical scientific priorities/training/engagement; analyze field insights; support field materials and education for emerging aficamten/HCM data.
- Build a US KOL HCM expert network and engage external experts for scientific exchange.
Qualifications:
- MD/DO or PharmD with 3–5 years Medical Affairs Medical Director experience (required). Cardiovascular training/clinical experience strongly preferred.
- Strong knowledge of Medical Affairs strategy (evidence generation, scientific communications, external engagement) and strong project management.
- Highly desirable: product approvals/launch/peri-launch experience.
- Preferred/desired: academic medicine/clinical research; familiarity with biostatistics/epidemiology; experience with vendor/budget/timeline management; medical plan development aligning objectives to product/org strategy.
- Familiarity with OPDP, PhRMA code, and key pharma regulations (plus).
- Ability to critically evaluate clinical trial data, literature, guidelines, and RWE; translate complex science into actionable guidance.
- Working knowledge of congress strategy, advisory boards, medical education, scientific communications; strong oral/written communication.
- Proficiency with Microsoft Office; travel ~30%.
Benefits (explicitly stated): equity (stock options/RSUs); comprehensive health/dental/vision/life/disability; 401k match; learning and wellness stipends; paid time off.
Application instructions: Review GDPR policy prior to applying.