Global Medical Director
Alnylam Pharmaceuticals
August 08, 2026
Remote friendly (Cambridge, MA)
United States
Medical Affairs
Role & Responsibilities:
- Provide strategic and scientific leadership; define global Medical Affairs strategy for CNS early-stage clinical programs (Huntington’s disease, CAA, Alzheimer’s).
- Serve as product development team member; influence clinical development plans, study design, and data interpretation.
- Lead global scientific engagement with key stakeholders; develop and maintain relationships with international scientific leaders.
- Organize global expert events (advisory boards, panels, symposia); act as scientific/medical expert internally and externally.
- Collaborate with clinical operations, commercial development, market access, clinical R&D, pharmacovigilance, and PRC (medical aspects).
- Provide medical insights for R&D and commercialization (patient pathways, treatment landscape, prescriber patterns).
- Lead Medical Affairs for strategic partnerships (evidence generation, medical communications/publications & congresses, medical training, omnichannel prelaunch strategy).
- Integrate global/regional Medical Affairs insights into product development.
- Oversee integrated evidence plans and ensure high-quality publications across development and launch.
- Provide TA strategy input to support Target Product Profiles (TPPs) and enable timely patient access.
Qualifications (Required/Preferred):
- MD/PhD/PharmD or equivalent ex-US medical degree.
- 5+ years in Medical Affairs and R&D; familiarity with early clinical development (pharma/biotech).
- Deep neurology/neurological disease expertise.
- Preferred: regulatory/policy/technology knowledge; global scientific engagement experience; RWE/diagnostics/translational/digital innovations.
- Strong matrix leadership; persuasive communication of complex data.
- Preferred: work with clinical development to shape CDP/data interpretation; due diligence & integrated asset planning; build medical assessment framework.
Comp/Benefits (as stated):
- U.S. Pay Range: $238,800.00–$323,000.00 base; eligible for annual short-term incentive and annual long-term incentive (e.g., equity).
- Benefits include medical/dental/vision, life/disability, lifestyle reimbursement, flexible spending/HSAs, 401(k) match, paid time off, wellness days, holidays, recharge breaks, and family leave.
- Provide strategic and scientific leadership; define global Medical Affairs strategy for CNS early-stage clinical programs (Huntington’s disease, CAA, Alzheimer’s).
- Serve as product development team member; influence clinical development plans, study design, and data interpretation.
- Lead global scientific engagement with key stakeholders; develop and maintain relationships with international scientific leaders.
- Organize global expert events (advisory boards, panels, symposia); act as scientific/medical expert internally and externally.
- Collaborate with clinical operations, commercial development, market access, clinical R&D, pharmacovigilance, and PRC (medical aspects).
- Provide medical insights for R&D and commercialization (patient pathways, treatment landscape, prescriber patterns).
- Lead Medical Affairs for strategic partnerships (evidence generation, medical communications/publications & congresses, medical training, omnichannel prelaunch strategy).
- Integrate global/regional Medical Affairs insights into product development.
- Oversee integrated evidence plans and ensure high-quality publications across development and launch.
- Provide TA strategy input to support Target Product Profiles (TPPs) and enable timely patient access.
Qualifications (Required/Preferred):
- MD/PhD/PharmD or equivalent ex-US medical degree.
- 5+ years in Medical Affairs and R&D; familiarity with early clinical development (pharma/biotech).
- Deep neurology/neurological disease expertise.
- Preferred: regulatory/policy/technology knowledge; global scientific engagement experience; RWE/diagnostics/translational/digital innovations.
- Strong matrix leadership; persuasive communication of complex data.
- Preferred: work with clinical development to shape CDP/data interpretation; due diligence & integrated asset planning; build medical assessment framework.
Comp/Benefits (as stated):
- U.S. Pay Range: $238,800.00–$323,000.00 base; eligible for annual short-term incentive and annual long-term incentive (e.g., equity).
- Benefits include medical/dental/vision, life/disability, lifestyle reimbursement, flexible spending/HSAs, 401(k) match, paid time off, wellness days, holidays, recharge breaks, and family leave.