Global Medical Director
Alnylam Pharmaceuticals
August 29, 2026
Remote friendly (Cambridge, MA)
United States
Medical Affairs
Key Responsibilities:
- Provide strategic and scientific leadership to define global Medical Affairs strategy for CNS early-stage clinical programs.
- Serve as a key product development team member impacting clinical development plans, study design, and data interpretation.
- Lead and execute global scientific engagement strategy with key stakeholders.
- Develop and maintain relationships with international scientific leaders to increase awareness of the early asset portfolio.
- Organize and manage global expert events (advisory boards, panels, symposia); act as internal/external scientific medical expert.
- Collaborate with clinical operations, commercial development, market access, clinical R&D, pharmacovigilance, and the promotion review committee (PRC) on medical aspects.
- Provide strategic medical insights into R&D and commercialization (patient pathways, treatment landscape, prescriber patterns).
- Lead Medical Affairs for strategic partnerships:
- Partner with Value & Evidence Strategy on integrated evidence generation plans.
- Partner with Medical Communications on global communication and timely scientific data (publications, congresses).
- Partner with Medical Training on scientific/skill-based training across regions.
- Partner with Omnichannel on Omnichannel prelaunch strategy.
- Liaise with global/regional Medical Affairs to integrate market insights into product development.
- Oversee comprehensive integrated evidence plans (IEPs) and ensure high-quality publications throughout development and in-market.
- Provide medical expertise for TA strategies to deliver data/label aligned to Target Product Profile (TPP) to enable speedy patient access.
Qualifications:
- MD, PhD, PharmD, or equivalent ex-US medical degree.
- 5+ years in Medical Affairs and R&D in pharma/biotech; experience in early clinical development.
- Deep knowledge/experience in Neurological Diseases.
- Extensive knowledge of latest regulatory, policy, and technology developments (preferred).
- Experience with global scientific engagement (congresses, experts/panels, symposia) (preferred).
- Influential matrix leadership; strong ability to communicate complex data.
- Experience with RWE, diagnostics, translational work, and digital innovations.
- Expertise informing R&D/commercial strategies (patient pathways, treatment landscape).
- Preferred: experience with clinical development teams to shape CDP, data interpretation, and dissemination.
- Experience supporting business development due diligence and integrated asset planning (medical assessment framework).
- Strong written/verbal communication, leadership, interpersonal skills; professionalism, maturity, confidentiality; recognized team leader-coach.
U.S. Pay Range:
- $238,800.00 - $323,000.00
- Eligible for annual short-term incentive and annual long-term incentive (e.g., equity).
Benefits (as stated): Medical, dental, vision, life/disability, lifestyle reimbursement, flexible spending/HSAs, 401(k) match, paid time off, wellness days, holidays, two recharge breaks, family resources/leave.
- Provide strategic and scientific leadership to define global Medical Affairs strategy for CNS early-stage clinical programs.
- Serve as a key product development team member impacting clinical development plans, study design, and data interpretation.
- Lead and execute global scientific engagement strategy with key stakeholders.
- Develop and maintain relationships with international scientific leaders to increase awareness of the early asset portfolio.
- Organize and manage global expert events (advisory boards, panels, symposia); act as internal/external scientific medical expert.
- Collaborate with clinical operations, commercial development, market access, clinical R&D, pharmacovigilance, and the promotion review committee (PRC) on medical aspects.
- Provide strategic medical insights into R&D and commercialization (patient pathways, treatment landscape, prescriber patterns).
- Lead Medical Affairs for strategic partnerships:
- Partner with Value & Evidence Strategy on integrated evidence generation plans.
- Partner with Medical Communications on global communication and timely scientific data (publications, congresses).
- Partner with Medical Training on scientific/skill-based training across regions.
- Partner with Omnichannel on Omnichannel prelaunch strategy.
- Liaise with global/regional Medical Affairs to integrate market insights into product development.
- Oversee comprehensive integrated evidence plans (IEPs) and ensure high-quality publications throughout development and in-market.
- Provide medical expertise for TA strategies to deliver data/label aligned to Target Product Profile (TPP) to enable speedy patient access.
Qualifications:
- MD, PhD, PharmD, or equivalent ex-US medical degree.
- 5+ years in Medical Affairs and R&D in pharma/biotech; experience in early clinical development.
- Deep knowledge/experience in Neurological Diseases.
- Extensive knowledge of latest regulatory, policy, and technology developments (preferred).
- Experience with global scientific engagement (congresses, experts/panels, symposia) (preferred).
- Influential matrix leadership; strong ability to communicate complex data.
- Experience with RWE, diagnostics, translational work, and digital innovations.
- Expertise informing R&D/commercial strategies (patient pathways, treatment landscape).
- Preferred: experience with clinical development teams to shape CDP, data interpretation, and dissemination.
- Experience supporting business development due diligence and integrated asset planning (medical assessment framework).
- Strong written/verbal communication, leadership, interpersonal skills; professionalism, maturity, confidentiality; recognized team leader-coach.
U.S. Pay Range:
- $238,800.00 - $323,000.00
- Eligible for annual short-term incentive and annual long-term incentive (e.g., equity).
Benefits (as stated): Medical, dental, vision, life/disability, lifestyle reimbursement, flexible spending/HSAs, 401(k) match, paid time off, wellness days, holidays, two recharge breaks, family resources/leave.