Executive Medical Director, Global Medical (Nephrology)
Vertex Pharmaceuticals
August 11, 2026
Remote friendly (Boston, MA)
United States
Medical Affairs
General Summary:
The Executive Medical Director, Global Medical Lead (GML), Nephrology provides global medical leadership for a designated disease area(s), accountable for global medical strategy/implementation and tracking of global activities.
Key Duties and Responsibilities:
Medical Strategy
- Lead Integrated Medical Plan development/execution/communication (medical strategy, global tactical plan, publication, congress, evidence generation) in collaboration with internal stakeholders.
- Ensure alignment with organizational and DST priorities; distill insights to inform strategy; establish/track medical KPIs.
- Apply structured problem-solving/root cause analysis; prioritize competing demands; develop/manage DA budget and fund allocation.
Scientific Excellence
- Serve as product/disease area expert and primary medical contact for global issues.
- Lead peer-reviewed publications, congress presentations, evidence generation, and global scientific communications/materials.
- Perform medical review of brand and global medical content per SOPs.
External Partnerships
- Represent the company at scientific/medical forums; engage thought leaders/key experts.
Medical Communication
- Tailor communication to stakeholder needs; deliver external medical presentations; support training.
- Interpret clinical data (trials, registries, literature).
Regional & Cross-Functional Collaboration
- Own medical component of go-to-market model; support regional launch/lifecycle training/materials.
- Drive internal alignment on medical content/messaging; lead DST-aligned medical efforts (GMAT chair).
- Provide Medical Affairs leadership to launch/global brand teams; represent Medical Affairs in label discussions; support Access/Policy/Advocacy/Corp Comms with medical/scientific expertise.
Evidence Generation & Access
- Lead integrated evidence generation and lifecycle management studies with HEOR; may act as medical monitor.
- Oversee ISS programs; review ISS protocols; lead MAP committees as applicable.
Team/People Management
- Recruit/develop/manage/coaching; inspire continuous development; address skill gaps; manage IDPs.
Compliance & Pharmacovigilance
- Ensure compliance with guidelines/Code/SOPs/GCP/ICH; ensure AE reporting readiness; support safety communications.
Qualifications:
- MD (preferred), PhD, PharmD, or other advanced life sciences degree required.
- Typically 10 years’ experience with 5 years supervisory/management experience (or equivalent).
- 6+ years relevant leadership in medical affairs and/or clinical development (global + country/region desired).
- 2+ years disease area industry experience or 2+ years clinical/academic disease area experience.
Benefits:
- Eligible for annual bonus and annual equity awards; may be eligible for overtime pay.
Application Instructions:
- Contact Talent Acquisition at ApplicationAssistance@vrtx.com for accommodation requests related to the hiring process.
The Executive Medical Director, Global Medical Lead (GML), Nephrology provides global medical leadership for a designated disease area(s), accountable for global medical strategy/implementation and tracking of global activities.
Key Duties and Responsibilities:
Medical Strategy
- Lead Integrated Medical Plan development/execution/communication (medical strategy, global tactical plan, publication, congress, evidence generation) in collaboration with internal stakeholders.
- Ensure alignment with organizational and DST priorities; distill insights to inform strategy; establish/track medical KPIs.
- Apply structured problem-solving/root cause analysis; prioritize competing demands; develop/manage DA budget and fund allocation.
Scientific Excellence
- Serve as product/disease area expert and primary medical contact for global issues.
- Lead peer-reviewed publications, congress presentations, evidence generation, and global scientific communications/materials.
- Perform medical review of brand and global medical content per SOPs.
External Partnerships
- Represent the company at scientific/medical forums; engage thought leaders/key experts.
Medical Communication
- Tailor communication to stakeholder needs; deliver external medical presentations; support training.
- Interpret clinical data (trials, registries, literature).
Regional & Cross-Functional Collaboration
- Own medical component of go-to-market model; support regional launch/lifecycle training/materials.
- Drive internal alignment on medical content/messaging; lead DST-aligned medical efforts (GMAT chair).
- Provide Medical Affairs leadership to launch/global brand teams; represent Medical Affairs in label discussions; support Access/Policy/Advocacy/Corp Comms with medical/scientific expertise.
Evidence Generation & Access
- Lead integrated evidence generation and lifecycle management studies with HEOR; may act as medical monitor.
- Oversee ISS programs; review ISS protocols; lead MAP committees as applicable.
Team/People Management
- Recruit/develop/manage/coaching; inspire continuous development; address skill gaps; manage IDPs.
Compliance & Pharmacovigilance
- Ensure compliance with guidelines/Code/SOPs/GCP/ICH; ensure AE reporting readiness; support safety communications.
Qualifications:
- MD (preferred), PhD, PharmD, or other advanced life sciences degree required.
- Typically 10 years’ experience with 5 years supervisory/management experience (or equivalent).
- 6+ years relevant leadership in medical affairs and/or clinical development (global + country/region desired).
- 2+ years disease area industry experience or 2+ years clinical/academic disease area experience.
Benefits:
- Eligible for annual bonus and annual equity awards; may be eligible for overtime pay.
Application Instructions:
- Contact Talent Acquisition at ApplicationAssistance@vrtx.com for accommodation requests related to the hiring process.