Executive Director, HEOR

Key result areas (major duties, accountabilities and responsibilities)
- Define the HEOR strategy for gene therapy programs
- Lead and conduct methodologically rigorous, feasible studies addressing priority HEOR evidence needs, including:
- Longitudinal retrospective studies using existing databases to assess patient characteristics, treatment patterns, and clinical/economic and/or patient-reported outcomes
- Retrospective or prospective evaluations of disease natural history and treatment patterns (including drug utilization and adherence)
- Cross-sectional surveys of patients, caregivers, healthcare providers/practitioners, and/or payers
- Assessments of burden of illness, patient preference studies, and/or comparative effectiveness
- Models of cost-effectiveness and budget impact; indirect treatment comparison models and methodologies
- Collaborate with Clinical Development to incorporate HEOR perspectives into the clinical development plan and provide input into clinical protocol design to capture HEOR endpoints relevant to payers, physicians, and patients
- Lead development of health economics models
- Develop product value narrative and educate internal/external stakeholders on product value proposition
- Prepare global value and reimbursement dossiers and oversee submission to relevant HTAs; support HTA/payer interactions
- Manage external vendors and HEOR budget to achieve deliverables
- Monitor global HTA/payer requirements and healthcare landscape to anticipate future internal/external resource needs
- Serve as HEOR subject matter expert in cross-functional teams; provide methodological/analytical expertise on real-world data
- Develop HEOR publications for scientific congresses and peer-reviewed journals
- Maintain knowledge of scientific, clinical, and commercial developments and payer pharmacy management/medical policy trends and techniques

Qualifications & Skills
- Advanced degree (MD, PhD, MS/MPH, or PharmD) in health economics, epidemiology, health services research, public health, scientific discipline, or related fields
- 8–10 years’ experience in HEOR and/or market access in pharma/biotech; rare disease and gene therapy experience strongly preferred
- Proven excellence in designing, conducting, and interpreting health economics and outcomes research, especially quality of life and patient-reported outcomes
- Background in Huntington’s Disease is a plus
- Significant experience with drug development and marketed products
- In-depth knowledge/experience with US/EU payer segments (HTAs, health plans, PBMs, providers, commercial, government)
- Ability to adhere to regulatory, legal, and compliance standards for Medical Affairs activities
- Travel up to 30% (US and internationally)
- Demonstrate alignment with company values
- Strong interpersonal skills and cross-functional leadership/influence
- Strong planning, prioritization, management, and organizational skills
- Ability to navigate ambiguous, complex situations
- Ability to interface with multiple stakeholders (clinicians and payers)
- Business and analytic skills; understanding of pharmaceutical practices impacting development and commercialization
- Ability to understand and make recommendations concerning evolving healthcare systems

Salary Range
- $275,000 – $332,000