Executive Director, Global Oncology Medical Affairs, Evidence Generation
Immunocore
August 24, 2026
Remote friendly (Radnor, PA)
United States
Medical Affairs
Main Purpose of Job
- Lead a cross-functional Evidence Generation matrix team and develop an Integrated Evidence Plan (IEP).
Key Responsibilities
- Lead data gap analysis and IEP development with R&D, Global Product Teams, Medical Affairs market leads, and stakeholders; provide thought leadership on evidence gaps and priorities.
- Execute non-registrational data generation (NRDG): sponsored NRDG trials, externally sponsored research (ESRs), collaborative research, non-interventional and real-world evidence.
- Manage identification/prioritization of data gaps, AOIs, and RFPs; ensure governance approvals, contracting, and budgeting.
- Ensure ESR milestones/timelines via ongoing engagement with sites, investigators, and networks.
- Align IEPs across portfolio (late-stage clinical through commercial, incl. life cycle management).
- Identify ESR areas of interest with HEOR and Translational Research; develop real-world data and publication plans.
- Lead registry data generation (e.g., Pulse OMNI and global collaborations) and collaborate with Insights & Analytics, Market Access, and HEOR on RWE/HEOR opportunities.
- Oversee clinical ESR execution and investigator mitigation; maintain awareness of non-clinical execution via TM team.
- Accountable for ESR and registry budget; maintain SOPs/policies/work instructions.
NRDG Sponsored Trials Capability (Phase IV)
- Build capability for sponsored trials to generate RWE: strategic planning, clinical study design, operational oversight (initiation to data readout), and publication planning; develop NRDG processes/SOPs; partner with Clinical Ops.
External Collaborations
- Build partnerships with cooperative groups/research networks (e.g., EORTC, SARC, CTEP, COG, etc.); support business development as needed.
Qualifications/Required Skills
- Advanced Clinical/Science degree (MD/PhD/PharmD).
- 5+ years in pharma or external expert partnership experience.
- Oncology experience (melanoma preferred).
- Experience developing medical data generation strategy and IEPs.
- Experience with interventional/non-interventional studies (e.g., Ph 3b/4, EAP, ESRs, observational).
- Strong matrix leadership, relationship building, public communication, negotiation, project management, budgeting.
- Knowledge of drug development/commercialization and regulatory standards.
- 25% travel required.
- Lead a cross-functional Evidence Generation matrix team and develop an Integrated Evidence Plan (IEP).
Key Responsibilities
- Lead data gap analysis and IEP development with R&D, Global Product Teams, Medical Affairs market leads, and stakeholders; provide thought leadership on evidence gaps and priorities.
- Execute non-registrational data generation (NRDG): sponsored NRDG trials, externally sponsored research (ESRs), collaborative research, non-interventional and real-world evidence.
- Manage identification/prioritization of data gaps, AOIs, and RFPs; ensure governance approvals, contracting, and budgeting.
- Ensure ESR milestones/timelines via ongoing engagement with sites, investigators, and networks.
- Align IEPs across portfolio (late-stage clinical through commercial, incl. life cycle management).
- Identify ESR areas of interest with HEOR and Translational Research; develop real-world data and publication plans.
- Lead registry data generation (e.g., Pulse OMNI and global collaborations) and collaborate with Insights & Analytics, Market Access, and HEOR on RWE/HEOR opportunities.
- Oversee clinical ESR execution and investigator mitigation; maintain awareness of non-clinical execution via TM team.
- Accountable for ESR and registry budget; maintain SOPs/policies/work instructions.
NRDG Sponsored Trials Capability (Phase IV)
- Build capability for sponsored trials to generate RWE: strategic planning, clinical study design, operational oversight (initiation to data readout), and publication planning; develop NRDG processes/SOPs; partner with Clinical Ops.
External Collaborations
- Build partnerships with cooperative groups/research networks (e.g., EORTC, SARC, CTEP, COG, etc.); support business development as needed.
Qualifications/Required Skills
- Advanced Clinical/Science degree (MD/PhD/PharmD).
- 5+ years in pharma or external expert partnership experience.
- Oncology experience (melanoma preferred).
- Experience developing medical data generation strategy and IEPs.
- Experience with interventional/non-interventional studies (e.g., Ph 3b/4, EAP, ESRs, observational).
- Strong matrix leadership, relationship building, public communication, negotiation, project management, budgeting.
- Knowledge of drug development/commercialization and regulatory standards.
- 25% travel required.