Executive Director, Global Medical Lead - HEME
Vertex Pharmaceuticals
June 27, 2026
Remote friendly (Boston, MA)
United States
Medical Affairs
Key Duties and Responsibilities
- Lead development, implementation, execution, and communication of Integrated Medical Plans (medical strategy, tactical plan, publication, congress, post-approval evidence generation) in collaboration with Clinical Development, HEOR, RWE, Medical Writing, and internal stakeholders.
- Align medical strategy with organizational objectives; integrate team goals with Vertex and DST priorities; distill insights into actionable outcomes.
- Establish and track medical KPIs; apply root-cause problem solving and prioritize competing demands.
- Accountable for global disease area budget, fund allocation, and tracking.
Scientific Excellence
- Serve as product/disease area expert and primary contact for global disease area issues externally and internally.
- Lead peer-reviewed publications, congress presentations, and evidence generation.
- Disseminate emerging data and lead global scientific communications/materials (symposia, advisory boards, training); review brand/global medical content aligned to SOPs.
External Partnerships & Medical Communication
- Represent Vertex at scientific/medical forums; engage key thought leaders.
- Deliver external medical presentations; support disease area training; interpret clinical data for pipeline/marketed medicines.
Collaboration, Commercial Support, Evidence & Compliance
- Own global go-to-market medical partnership and commercialization medical alignment; chair GMAT and drive deliverables.
- Provide Medical Affairs leadership for Launch/Global Brand Teams; represent Medical Affairs in label discussions.
- Lead lifecycle evidence generation with HEOR; oversee ISS programs; act as medical monitor as applicable; lead Managed Access activities.
- Ensure compliance with global/regional guidelines, Code of Conduct, SOPs, GCP, and ICH; ensure adverse event identification/reporting.
Team/People Management
- Recruit, develop, manage, and coach the global medical team; identify skill gaps; manage performance cycles and development plans.
Education and Experience
- Required: MD/PhD/PharmD or other advanced life sciences degree.
- Typically: 15 years total experience; 7 years supervisory/management.
- 6+ years leadership in Medical Affairs and/or Clinical Development; 2+ years disease area industry experience.
Pay/Benefits (as stated)
- Pay range: $328,000–$492,000.
- Eligible for annual bonus and annual equity awards; benefits include medical/dental/vision, generous paid time off (incl. week-long Summer/Winter shutdown), educational assistance/student loan repayment, commuting subsidy, matching charitable donations, 401(k).
- Flex designation: Hybrid (remote up to 2 days/week) or On-Site (5 days/week on-site with ad hoc flexibility).
- Lead development, implementation, execution, and communication of Integrated Medical Plans (medical strategy, tactical plan, publication, congress, post-approval evidence generation) in collaboration with Clinical Development, HEOR, RWE, Medical Writing, and internal stakeholders.
- Align medical strategy with organizational objectives; integrate team goals with Vertex and DST priorities; distill insights into actionable outcomes.
- Establish and track medical KPIs; apply root-cause problem solving and prioritize competing demands.
- Accountable for global disease area budget, fund allocation, and tracking.
Scientific Excellence
- Serve as product/disease area expert and primary contact for global disease area issues externally and internally.
- Lead peer-reviewed publications, congress presentations, and evidence generation.
- Disseminate emerging data and lead global scientific communications/materials (symposia, advisory boards, training); review brand/global medical content aligned to SOPs.
External Partnerships & Medical Communication
- Represent Vertex at scientific/medical forums; engage key thought leaders.
- Deliver external medical presentations; support disease area training; interpret clinical data for pipeline/marketed medicines.
Collaboration, Commercial Support, Evidence & Compliance
- Own global go-to-market medical partnership and commercialization medical alignment; chair GMAT and drive deliverables.
- Provide Medical Affairs leadership for Launch/Global Brand Teams; represent Medical Affairs in label discussions.
- Lead lifecycle evidence generation with HEOR; oversee ISS programs; act as medical monitor as applicable; lead Managed Access activities.
- Ensure compliance with global/regional guidelines, Code of Conduct, SOPs, GCP, and ICH; ensure adverse event identification/reporting.
Team/People Management
- Recruit, develop, manage, and coach the global medical team; identify skill gaps; manage performance cycles and development plans.
Education and Experience
- Required: MD/PhD/PharmD or other advanced life sciences degree.
- Typically: 15 years total experience; 7 years supervisory/management.
- 6+ years leadership in Medical Affairs and/or Clinical Development; 2+ years disease area industry experience.
Pay/Benefits (as stated)
- Pay range: $328,000–$492,000.
- Eligible for annual bonus and annual equity awards; benefits include medical/dental/vision, generous paid time off (incl. week-long Summer/Winter shutdown), educational assistance/student loan repayment, commuting subsidy, matching charitable donations, 401(k).
- Flex designation: Hybrid (remote up to 2 days/week) or On-Site (5 days/week on-site with ad hoc flexibility).