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Enterprise Programs - Senior Program Manager

Amgen
Full-time
Remote friendly (United States)
United States

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Role Summary

Enterprise Programs - Senior Program Manager

Let’s do this. Let’s change the world. In this vital role you will lead strategic, business-driven technology initiatives that deliver measurable outcomes and business value. This role is ideal for a seasoned program leader with a strong understanding of both business processes and enterprise technology. You will oversee a portfolio of transformational initiatives aimed at enabling innovation, improving operational efficiency, and advancing data-driven decision making.

Responsibilities

  • Lead delivery of complex programs that align to enterprise goals and deliver measurable value
  • Drive transformational programs to deliver on business priorities
  • Work closely with business stakeholders to define outcomes, ensure solutions are implemented as planned and drive adoption
  • Translate business needs into executable program plans, including scope, timelines, resource planning, and budget oversight
  • Partner with cross-functional teams including data & analytics, enterprise applications, and digital product teams to deliver outcomes
  • Manage program governance, steering committees, and status reporting for senior partners
  • Drive structured methodologies such as Agile, SAFe, or hybrid approaches to improve delivery efficiency and responsiveness
  • Track program KPIs, ROI, and performance metrics aligned to business success criteria
  • Coordinate organizational change, business readiness, and stakeholder engagement activities across functions and geographies
  • Build trust and alignment across technology teams and business leaders to sustain long-term strategic partnerships
  • Apply continuous improvement practices to program execution and delivery frameworks.

Qualifications

  • Basic Qualifications:
    • Doctorate degree and 2 years of Scientific and/or IT Operations and/or Business experience
    • Or Master’s degree and 4 years of Scientific and/or IT Operations and/or Business experience
    • Or Bachelor’s degree and 6 years of Scientific and/or IT Operations and/or Business experience
    • Or Associate’s degree and 10 years of Scientific and/or IT Operations and/or Business experience
    • Or High school diploma / GED and 12 years of Scientific and/or IT Operations and/or Business experience
  • Preferred Qualifications:
    • 6–10 years of experience delivering business technology solutions and programs in a matrixed, global organization
    • Demonstrated success in aligning technology execution with business strategy to achieve measurable outcomes
    • Experience leading transformational programs or M&A
    • Experience leading programs involving business process optimization, digital product rollouts, enterprise applications, or analytics platforms
    • Proficiency with program and portfolio management tools (e.g., Smartsheet, JIRA, ServiceNow, Confluence) and executive reporting dashboards
    • Strong stakeholder engagement, communication, and change leadership skills across business and technical audiences
    • Ability to manage vendor relationships and third-party service providers in a co-delivery model
    • Familiarity with data privacy, GxP, and regulatory compliance frameworks in a life sciences context
    • PMP, SAFe, Agile, or Lean certification preferred

Skills

  • Strategic program leadership
  • Enterprise technology knowledge
  • Cross-functional collaboration
  • Change management
  • Agile, SAFe, or hybrid delivery frameworks
  • Vendor and stakeholder management
  • Data-driven decision making

Education

  • Doctorate, Master’s, Bachelor’s, Associate’s, or High School diploma with corresponding experience as listed in Basic Qualifications

Additional Requirements

  • None beyond those listed in qualifications
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