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Director, Medical Science Liaisons

Praxis Precision Medicines, Inc.
August 26, 2026
Remote friendly (Boston, MA)
United States
Medical Affairs
Primary Responsibilities
- Lead and develop a high-performing MSL team; set expectations for scientific excellence, stakeholder engagement, insight generation, accountability, and results; provide hands-on coaching via field visits, joint engagements, feedback, and individualized development.
- Serve as a player-coach, maintaining direct, trusted scientific relationships with priority neurologists and movement disorder specialists, investigators, advanced practice providers, and other stakeholders.
- Translate Medical Affairs strategy into field execution (regional stakeholder planning, strategic account planning, resource deployment) across pre-launch, potential launch, and post-launch priorities for essential tremor.
- Drive high-quality scientific exchange and external engagement (advisory boards, congresses, and scientific meetings) around essential tremor, emerging clinical data, and evolving treatment paradigms.
- Convert field intelligence into action by synthesizing emerging questions, unmet needs, clinical practice changes, patient-care barriers, and insights for Medical Affairs and cross-functional strategy.
- Partner cross-functionally (Medical Affairs, Clinical Development, Commercial, Market Access) with scientific/clinical context on disease burden, patient journeys, treatment pathways, evidence needs, and access.
- Build a compliant, accountable field organization (recruitment, onboarding, training, performance management, field effectiveness, launch readiness, resource planning; adherence to regulatory requirements, industry standards, company policies, and SOPs).

Qualifications and Key Success Factors
- Advanced clinical/scientific degree (PharmD, PhD, MD, NP, PA, RN, or equivalent).
- Prior MSL experience with demonstrated success in field-based Medical Affairs.
- People leadership experience (coach/develop/hold team accountable while maintaining scientific credibility).
- Neurology/CNS experience required; movement disorders experience (essential tremor or Parkinson’s) preferred.
- Pre-launch and/or launch Medical Affairs experience strongly preferred.
- Ability to build therapeutic expertise, translate complex science to field strategy, and engage external experts.
- Strong strategic judgment, account planning, insight generation, and cross-functional collaboration.
- Market Access/payer & access experience preferred.
- High ownership; comfortable with autonomy and ambiguity; strong prioritization and execution.
- Strong relationships with healthcare professionals and scientific experts.
- Willingness and ability to travel extensively.

Annualized Base Salary: $228,000 USD - $248,000 USD

Compensation & Benefits
- 99% of premium paid for medical, dental, and vision; company-paid life insurance, AD&D, disability; voluntary benefits.
- 401(k) match up to 6%; long-term stock incentives and ESPP; discretionary quarterly bonus; wellness benefit; generous PTO; paid holidays and company-wide shutdowns.