Director, HR Business Partner
Denali Therapeutics
September 25, 2026
Full-time
On-site
South San Francisco, CA
Human Resources
Role: Director, Human Resources Business Partner supporting Denali's biotech operations, focusing on developing and executing HR strategies aligned with organizational goals. Responsibilities: serve as a senior business partner and advisor; collaborate on organizational design, talent acquisition, learning, compensation, benefits, and employee relations; assess internal talent needs; facilitate employee growth and retention; support compensation and benefits strategies; address performance gaps; leverage HR systems and analytics; lead people-focused initiatives to enhance engagement, connection, growth, and inclusion. Requirements: Bachelorβs degree; 15+ years of broad HR experience, including 5+ years in HR business partnering; experience in team-building, HR program development, and implementation; proficiency in HRIS and ATS tools; pharmaceutical/biotech experience preferred. HighValue: biotech/biopharma industry experience, full-time on-site in South San Francisco, strategic HR leadership, organizational development, talent management, employee engagement, inclusion initiatives.