Director, Global Medical Lead, Zasocitinib – Psoriatic Arthritis (PsA)
Takeda
August 26, 2026
Remote friendly (Cambridge, MA)
United States
$192,400 - $302,390 USD yearly
Medical Affairs
Objectives:
- Accountable for development, implementation, and ongoing optimization of the global medical strategy for zasocitinib in PsA.
- Provide Director-level medical leadership and strategic counsel on product profile, data interpretation, benefit-risk, evidence gaps, and external scientific dynamics.
- Lead the global PsA Medical Strategy Team; coordinate medical sub-teams and matrix partners for integrated, timely execution.
- Define the medical evidence and scientific communications plan; translate insights from patients, HCPs, and external experts into action.
- Enable global-to-local medical strategy deployment with regional/affiliate medical teams while considering local practice, access, regulatory, and stakeholder needs.
- Model scientific excellence, inclusive collaboration, compliance, accountability, and patient focus; mentor matrix colleagues.
Accountabilities:
- Global medical lead and single-point medical accountable leader for zasocitinib in PsA (reporting to GMUH, Rheumatology).
- Partner to define and execute a multi-year global medical vision, integrated strategy, and evidence plan across the PsA lifecycle.
- Translate PsA science, patient unmet need, and stakeholder insights into medical priorities (launch preparedness, evidence generation, scientific communications, lifecycle opportunities).
- Lead a global cross-functional medical matrix across Clinical Development, Regulatory, Pharmacovigilance, Commercial, Market Access, HEOR, DD&T, regions, and affiliates.
- Chair/lead MST workstreams; provide medical recommendations, risk assessments, and decision input to GPT and governance forums.
- Establish strategic priorities/milestones/KPIs; monitor execution, resolve barriers, and escalate risks.
- Act as scientific steward for scientifically rigorous, compliant, patient-centered content and engagement; oversee evidence-generation strategy (RWE, investigator-sponsored research, partnerships, publications).
- Build relationships with thought leaders, societies, patient advocacy groups; represent Takeda in high-impact forums.
- Provide senior medical review/approval input for scientific and promotional/non-promotional materials; manage medical/evidence/safety/regulatory/reputational risks.
- Champion responsible use of digital/data science/AI to strengthen insight generation and patient/HCP experience.
Education/Experience & Qualifications:
- Required: advanced scientific/clinical degree (MD, DO, MBBS, PharmD, PhD, or equivalent). Strongly preferred: rheumatology/immunology/dermatology specialist experience.
- Typically 8–12+ years in biopharmaceutical medical affairs, clinical development, or related; meaningful global/regional strategic leadership.
- Strong experience leading medical strategy/execution in a matrixed organization; pre-launch/launch and/or lifecycle-management preferred.
- Proven expertise in rheumatology, immunology, and/or psoriatic arthritis.
- Required: evidence generation, publications, scientific communications, external expert engagement, global medical governance.
- Working knowledge of global pharmaceutical laws, regulations, and industry medical/commercial boundary requirements.
- Preferred: digital/analytics/AI-enabled approaches.
Skills:
- Strategic and enterprise mindset; ability to interpret clinical/safety/RWE/competitive data and communicate clearly to technical/non-technical audiences.
- Ability to influence senior stakeholders in a global matrix; judgment/integrity in regulated environments.
- Strong partnerships with external experts and internal cross-functional leaders; business/operational acumen.
- Exceptional written/verbal/presentation/executive communication across cultures.
- Commitment to patient centricity, inclusion, scientific excellence.
Benefits:
- U.S. based employees may be eligible for medical, dental, vision, 401(k) match, disability, life insurance, tuition reimbursement, paid volunteer time off, holidays, well-being benefits; up to 80 hours sick time and up to 120 hours paid vacation for new hires.
Application instructions:
- By clicking “Apply,” employment application process with Takeda will commence and application information will be processed per Takeda’s Privacy Notice and Terms of Use.
- Accountable for development, implementation, and ongoing optimization of the global medical strategy for zasocitinib in PsA.
- Provide Director-level medical leadership and strategic counsel on product profile, data interpretation, benefit-risk, evidence gaps, and external scientific dynamics.
- Lead the global PsA Medical Strategy Team; coordinate medical sub-teams and matrix partners for integrated, timely execution.
- Define the medical evidence and scientific communications plan; translate insights from patients, HCPs, and external experts into action.
- Enable global-to-local medical strategy deployment with regional/affiliate medical teams while considering local practice, access, regulatory, and stakeholder needs.
- Model scientific excellence, inclusive collaboration, compliance, accountability, and patient focus; mentor matrix colleagues.
Accountabilities:
- Global medical lead and single-point medical accountable leader for zasocitinib in PsA (reporting to GMUH, Rheumatology).
- Partner to define and execute a multi-year global medical vision, integrated strategy, and evidence plan across the PsA lifecycle.
- Translate PsA science, patient unmet need, and stakeholder insights into medical priorities (launch preparedness, evidence generation, scientific communications, lifecycle opportunities).
- Lead a global cross-functional medical matrix across Clinical Development, Regulatory, Pharmacovigilance, Commercial, Market Access, HEOR, DD&T, regions, and affiliates.
- Chair/lead MST workstreams; provide medical recommendations, risk assessments, and decision input to GPT and governance forums.
- Establish strategic priorities/milestones/KPIs; monitor execution, resolve barriers, and escalate risks.
- Act as scientific steward for scientifically rigorous, compliant, patient-centered content and engagement; oversee evidence-generation strategy (RWE, investigator-sponsored research, partnerships, publications).
- Build relationships with thought leaders, societies, patient advocacy groups; represent Takeda in high-impact forums.
- Provide senior medical review/approval input for scientific and promotional/non-promotional materials; manage medical/evidence/safety/regulatory/reputational risks.
- Champion responsible use of digital/data science/AI to strengthen insight generation and patient/HCP experience.
Education/Experience & Qualifications:
- Required: advanced scientific/clinical degree (MD, DO, MBBS, PharmD, PhD, or equivalent). Strongly preferred: rheumatology/immunology/dermatology specialist experience.
- Typically 8–12+ years in biopharmaceutical medical affairs, clinical development, or related; meaningful global/regional strategic leadership.
- Strong experience leading medical strategy/execution in a matrixed organization; pre-launch/launch and/or lifecycle-management preferred.
- Proven expertise in rheumatology, immunology, and/or psoriatic arthritis.
- Required: evidence generation, publications, scientific communications, external expert engagement, global medical governance.
- Working knowledge of global pharmaceutical laws, regulations, and industry medical/commercial boundary requirements.
- Preferred: digital/analytics/AI-enabled approaches.
Skills:
- Strategic and enterprise mindset; ability to interpret clinical/safety/RWE/competitive data and communicate clearly to technical/non-technical audiences.
- Ability to influence senior stakeholders in a global matrix; judgment/integrity in regulated environments.
- Strong partnerships with external experts and internal cross-functional leaders; business/operational acumen.
- Exceptional written/verbal/presentation/executive communication across cultures.
- Commitment to patient centricity, inclusion, scientific excellence.
Benefits:
- U.S. based employees may be eligible for medical, dental, vision, 401(k) match, disability, life insurance, tuition reimbursement, paid volunteer time off, holidays, well-being benefits; up to 80 hours sick time and up to 120 hours paid vacation for new hires.
Application instructions:
- By clicking “Apply,” employment application process with Takeda will commence and application information will be processed per Takeda’s Privacy Notice and Terms of Use.