Director, Global Health Economics & Outcomes Research (HEOR)
Dyne Therapeutics
13 hours ago
Remote friendly (Waltham, MA)
United States
$210,000 - $252,000 USD yearly
Market Access
Primary Responsibilities Include
- Informing development strategies from HEOR / market access perspective
- Represent the HEOR and market access perspective in internal clinical development and regulatory forums
- Provide critical input into clinical development plans, including protocol design, endpoint selection, and other aspects of clinical trial evidence generation, to ensure alignment with future payer and HTA expectations
- Communicate value to payers and HTA bodies
- Lead development of AMCP dossiers for US payers
- Lead development of cost-effectiveness models for NICE and other HTA bodies requiring formal cost-effectiveness analyses
- Serve as a core team member for HTA submissions outside the US: shape and stress-test value narratives included in pricing and reimbursement dossiers; interpret and recommend evidence to support such narratives
- Contribute to payer communication materials (e.g., Medical Value Liaison slide decks) and launch readiness activities as needed
- Lead real-world evidence (RWE) strategy and execution of real-world analyses
- Plan RWE generation activities to address evidence gaps for payers, HTA bodies, and clinicians
- Oversee execution of real-world data analyses to ensure analytical rigor and fitness for purpose
- Interpret and translate RWE results into peer-reviewed publications and other external communications to inform clinical practice and payer/HTA decision-making
Education and Skills Requirements (Qualifications)
- Bachelor’s degree or equivalent experience in economics, public health, epidemiology, biostatistics, health policy, life sciences, or a related discipline
- Advanced degrees (Master’s, PhD, PharmD, MD) welcome but not required
- 10+ years of progressive experience in HEOR, health analytics, value demonstration, market access, or closely related quantitative/scientific fields
- Demonstrated success leading complex evidence-generation, modeling, or analytical programs in biopharma, healthcare consulting, payer organizations, or academic research
- Experience influencing senior leaders and driving strategic decisions through evidence and structured analysis
Required Skills / Qualities
- Analytical ability and structured problem-solving
- Sophisticated understanding of evidence robustness and limits of analytical methodologies
- Understanding of value frameworks for medicine valuation, pricing, and reimbursement
- Strong mathematical intuition and model/assumption understanding
- Ability to read, interpret, and critique medical/scientific/health economics literature
- Biological and clinical literacy to engage with development teams and clinical experts
- Results orientation (rigor with pragmatism)
- Bias toward solutions, alternatives, and maintaining momentum
- Informing development strategies from HEOR / market access perspective
- Represent the HEOR and market access perspective in internal clinical development and regulatory forums
- Provide critical input into clinical development plans, including protocol design, endpoint selection, and other aspects of clinical trial evidence generation, to ensure alignment with future payer and HTA expectations
- Communicate value to payers and HTA bodies
- Lead development of AMCP dossiers for US payers
- Lead development of cost-effectiveness models for NICE and other HTA bodies requiring formal cost-effectiveness analyses
- Serve as a core team member for HTA submissions outside the US: shape and stress-test value narratives included in pricing and reimbursement dossiers; interpret and recommend evidence to support such narratives
- Contribute to payer communication materials (e.g., Medical Value Liaison slide decks) and launch readiness activities as needed
- Lead real-world evidence (RWE) strategy and execution of real-world analyses
- Plan RWE generation activities to address evidence gaps for payers, HTA bodies, and clinicians
- Oversee execution of real-world data analyses to ensure analytical rigor and fitness for purpose
- Interpret and translate RWE results into peer-reviewed publications and other external communications to inform clinical practice and payer/HTA decision-making
Education and Skills Requirements (Qualifications)
- Bachelor’s degree or equivalent experience in economics, public health, epidemiology, biostatistics, health policy, life sciences, or a related discipline
- Advanced degrees (Master’s, PhD, PharmD, MD) welcome but not required
- 10+ years of progressive experience in HEOR, health analytics, value demonstration, market access, or closely related quantitative/scientific fields
- Demonstrated success leading complex evidence-generation, modeling, or analytical programs in biopharma, healthcare consulting, payer organizations, or academic research
- Experience influencing senior leaders and driving strategic decisions through evidence and structured analysis
Required Skills / Qualities
- Analytical ability and structured problem-solving
- Sophisticated understanding of evidence robustness and limits of analytical methodologies
- Understanding of value frameworks for medicine valuation, pricing, and reimbursement
- Strong mathematical intuition and model/assumption understanding
- Ability to read, interpret, and critique medical/scientific/health economics literature
- Biological and clinical literacy to engage with development teams and clinical experts
- Results orientation (rigor with pragmatism)
- Bias toward solutions, alternatives, and maintaining momentum