Dir/Senior Director, Toxicology & Preclinical Pharmacology

Role: Senior/Director-level lead in preclinical pharmacology and toxicology for obesity and metabolic disease therapies, supporting peptide and small-molecule candidates from discovery through IND. Responsibilities: design, oversee, and interpret in vitro/in vivo GLP and non-GLP toxicology studies, safety pharmacology, and juvenile/reproductive toxicology; lead CRO interactions; integrate pharmacology, toxicokinetic, pathology, and biomarker data for development decisions; contribute to regulatory submissions including INDs and NDAs; collaborate with clinical teams on dose and risk assessments; mentor junior staff and support strategic planning for next-generation therapies. Requirements: PhD, DVM, PharmD, or equivalent in Pharmacology, Toxicology, or related field; 10+ years in biotech/pharma; expertise in metabolic disease pharmacology, GLP toxicology, and translational science; experience supporting IND-enabling programs; familiarity with regulatory guidelines; knowledge of peptide and small-molecule development. HighValue: metabolic disease, obesity, GLP toxicology, peptide and small-molecule modalities, IND/early clinical development, regulatory interactions, external CRO management. WorkSetup: hybrid/remote/onsite options.