Associate Medical / Medical Director - Cardiovascular
Edgewise Therapeutics
August 19, 2026
Remote friendly (United States)
United States
$240,000 - $325,000 USD yearly
Medical Affairs
About the Position: The Associate Director / Director of Clinical Development will play a pivotal role in advancing cardiovascular clinical programs and partnering with Clinical Development to shape strategy, drive operational excellence, and ensure consistent implementation.
Essential Job Duties and Functions:
- Contribute to clinical development strategy for HCM and HFpEF (operational excellence and innovation).
- Partner with Clinical Operations to support trial execution, including medical communications with clinical investigators.
- Engage trial sites/investigators to support patient enrollment and retention (Phase 2/Phase 3).
- Support advisory boards (Scientific Advisory Committee) and DMC meetings for assigned programs.
- Analyze/summarize clinical data to inform safety, efficacy, regulatory filings, study reports, and publications.
- Draft clinical sections of regulatory submissions (INDs, briefing documents, BLAs) and prepare for FDA/EMA meetings.
- Work with regulatory colleagues on documents and FDA/EMA responses.
- Contribute to development/refinement of Phase 2 HFpEF and Phase 3 HCM protocols.
- Serve as medical monitor to help ensure participant safety.
- Represent the company in external scientific/medical conferences as needed.
- Provide clinical insights to the commercial team by reviewing market research questions.
- Adhere to workplace health and safety policies and company procedures.
- Perform additional responsibilities as assigned.
Required Education, Experience and Skills:
- MD or MD/PhD with clinical trial experience.
- Minimum 2 years in drug development (industry) or equivalent academia biomedical research.
- Proven success leading clinical studies and protocol development.
- Strong scientific scholarship; expertise in clinical medicine and biomedical research.
- Excellent interpersonal and collaborative skills; exceptional verbal/written/presentation skills.
- Travel up to 20%.
Salary range: $240,000 - $325,000 (commensurate with experience).
Essential Job Duties and Functions:
- Contribute to clinical development strategy for HCM and HFpEF (operational excellence and innovation).
- Partner with Clinical Operations to support trial execution, including medical communications with clinical investigators.
- Engage trial sites/investigators to support patient enrollment and retention (Phase 2/Phase 3).
- Support advisory boards (Scientific Advisory Committee) and DMC meetings for assigned programs.
- Analyze/summarize clinical data to inform safety, efficacy, regulatory filings, study reports, and publications.
- Draft clinical sections of regulatory submissions (INDs, briefing documents, BLAs) and prepare for FDA/EMA meetings.
- Work with regulatory colleagues on documents and FDA/EMA responses.
- Contribute to development/refinement of Phase 2 HFpEF and Phase 3 HCM protocols.
- Serve as medical monitor to help ensure participant safety.
- Represent the company in external scientific/medical conferences as needed.
- Provide clinical insights to the commercial team by reviewing market research questions.
- Adhere to workplace health and safety policies and company procedures.
- Perform additional responsibilities as assigned.
Required Education, Experience and Skills:
- MD or MD/PhD with clinical trial experience.
- Minimum 2 years in drug development (industry) or equivalent academia biomedical research.
- Proven success leading clinical studies and protocol development.
- Strong scientific scholarship; expertise in clinical medicine and biomedical research.
- Excellent interpersonal and collaborative skills; exceptional verbal/written/presentation skills.
- Travel up to 20%.
Salary range: $240,000 - $325,000 (commensurate with experience).