Associate Medical Director
C4 Therapeutics, Inc.
August 25, 2026
Remote friendly (Watertown, MA)
United States
$230,938 - $255,245 USD yearly
Medical Affairs
Your Role / Responsibilities:
- Drive oncology development programs by refining clinical study protocols from Phase I through pivotal studies supporting regulatory submissions.
- Collaborate with cross-functional teams (Clinical Operations, Regulatory Affairs, Biostatistics) to align on clinical strategy and study design.
- Serve as medical monitor for assigned relapsed refractory multiple myeloma clinical trials, providing medical oversight, addressing protocol conduct and subject safety issues to ensure timely, high-quality data.
- Guide recruitment, study conduct, and dose escalation/early signals of activity appropriate to trial stage.
- Assess overall safety information for studies/compound with Pharmacovigilance.
- Develop and maintain relationships with key opinion leaders, investigators, and clinical trial sites.
- With the Senior Medical Director, provide input to global regulatory filings (IB clinical sections, INDs, CTAs, NDAs).
- Engage academic investigators; support site initiation visits and lead investigator meetings.
- Assist Pharmacovigilance with reviewing/interpreting clinical data for accuracy, context, and patient safety.
- Represent C4T in the scientific community; contribute to publication plans and build external expert relationships.
Required:
- M.D. (or internationally recognized equivalent) and at least 1 year of clinical research experience in pharma/CRO/consulting or academia.
- Ability to balance strategic vision with hands-on execution; work collaboratively in a fast-paced matrix and independently as needed.
- Exceptional scientific communication; active listening and stakeholder alignment.
- Strong interpersonal/negotiating skills; proactive issue prediction and decision-driving via diplomacy.
- Strong analytical/problem-solving skills with attention to detail.
Preferred:
- Clinical development experience (biotech/pharma), including companion diagnostics, clinical operations, and pharmacovigilance.
- Oncology and/or hematology experience (practice or life sciences).
Compensation:
- Base pay range: $230,938.00–$255,245.00 annually (varies by factors such as knowledge, skills, experience).
- Drive oncology development programs by refining clinical study protocols from Phase I through pivotal studies supporting regulatory submissions.
- Collaborate with cross-functional teams (Clinical Operations, Regulatory Affairs, Biostatistics) to align on clinical strategy and study design.
- Serve as medical monitor for assigned relapsed refractory multiple myeloma clinical trials, providing medical oversight, addressing protocol conduct and subject safety issues to ensure timely, high-quality data.
- Guide recruitment, study conduct, and dose escalation/early signals of activity appropriate to trial stage.
- Assess overall safety information for studies/compound with Pharmacovigilance.
- Develop and maintain relationships with key opinion leaders, investigators, and clinical trial sites.
- With the Senior Medical Director, provide input to global regulatory filings (IB clinical sections, INDs, CTAs, NDAs).
- Engage academic investigators; support site initiation visits and lead investigator meetings.
- Assist Pharmacovigilance with reviewing/interpreting clinical data for accuracy, context, and patient safety.
- Represent C4T in the scientific community; contribute to publication plans and build external expert relationships.
Required:
- M.D. (or internationally recognized equivalent) and at least 1 year of clinical research experience in pharma/CRO/consulting or academia.
- Ability to balance strategic vision with hands-on execution; work collaboratively in a fast-paced matrix and independently as needed.
- Exceptional scientific communication; active listening and stakeholder alignment.
- Strong interpersonal/negotiating skills; proactive issue prediction and decision-driving via diplomacy.
- Strong analytical/problem-solving skills with attention to detail.
Preferred:
- Clinical development experience (biotech/pharma), including companion diagnostics, clinical operations, and pharmacovigilance.
- Oncology and/or hematology experience (practice or life sciences).
Compensation:
- Base pay range: $230,938.00–$255,245.00 annually (varies by factors such as knowledge, skills, experience).