Skip to main content
AstraZeneca logo

US Medical Head, Early Assets

AstraZeneca
August 21, 2026
Full-time
On-site
Wilmington, DE
Medical Affairs
Role: US Medical Head of Early Assets at AstraZeneca, leading medical strategies for the company's early pipeline assets to influence development, regulatory, and commercial decisions. Responsibilities include developing translational and clinical development plans, acting as internal medical authority, shaping scientific narratives for product launches, and guiding study design to support US access and labeling. The role also involves building external networks, engaging in evidence generation activities, and integrating US perspectives into global development plans. Qualifications: Advanced scientific degree (MBBS, PharmD, PhD, or MD), with 5+ years in pharma or relevant health system roles, demonstrating expertise in cardiovascular, metabolic (notably obesity/weight management), immunology, or cell therapy. Proven experience in clinical trial conduct (Ph2/Ph3), RWE, and US regulatory strategy. Preferred: Global R&D experience or early asset development background, and cross-functional collaboration skills. High-Value: Focus on early pipeline assets, translational research, evidence generation, and regulatory strategy within CV and metabolism areas. Work environment: On-site with a flexible, collaborative, fast-paced setting. No specific travel requirements are stated.