Upstream Process Development Co-Op
Keros Therapeutics
September 02, 2026
Remote friendly (Lexington, MA)
United States
Operations
Job Summary
This role is responsible for media and feed preparation, execution of experiments for upstream biologics process development, routine daily maintenance of upstream equipment, and experiment data management and analysis. Organizational skills, communication skills, and recordkeeping are also critical.
Primary Responsibilities
- CHO mammalian cell cultures in shaker flasks, WAVE bioreactors, and benchtop bioreactors
- Media and feed formulation as needed for experiments
- Data management and analysis (metabolite, gas, cell count, and titer data)
- Media and feed studies to support process development on early phase programs
- Scale-down modeling and range finding for development and technology transfers
- Depth filtration filter loading studies to develop cell culture harvest strategies
- Routine maintenance on upstream equipment to maintain daily functionality
Core Competencies (Required Skills)
- Aseptic technique
- Experiment design
- Microsoft Office, especially Excel
- Technical and scientific writing and presentation skills
Preferred Skills
- Mammalian cell culture
- Media and buffer preparation
- Understanding of basic engineering and biology concepts
Education Requirements
- Currently enrolled in a chemical engineering, bioengineering, molecular biology, or related program to earn a Bachelor of Science degree or equivalent.
This role is responsible for media and feed preparation, execution of experiments for upstream biologics process development, routine daily maintenance of upstream equipment, and experiment data management and analysis. Organizational skills, communication skills, and recordkeeping are also critical.
Primary Responsibilities
- CHO mammalian cell cultures in shaker flasks, WAVE bioreactors, and benchtop bioreactors
- Media and feed formulation as needed for experiments
- Data management and analysis (metabolite, gas, cell count, and titer data)
- Media and feed studies to support process development on early phase programs
- Scale-down modeling and range finding for development and technology transfers
- Depth filtration filter loading studies to develop cell culture harvest strategies
- Routine maintenance on upstream equipment to maintain daily functionality
Core Competencies (Required Skills)
- Aseptic technique
- Experiment design
- Microsoft Office, especially Excel
- Technical and scientific writing and presentation skills
Preferred Skills
- Mammalian cell culture
- Media and buffer preparation
- Understanding of basic engineering and biology concepts
Education Requirements
- Currently enrolled in a chemical engineering, bioengineering, molecular biology, or related program to earn a Bachelor of Science degree or equivalent.