Upstream Process Development Co-Op
Keros Therapeutics
Full-time
On-site
Lexington, MA
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Role Summary
Upstream Process Development Co-Op at Keros Therapeutics. Responsible for media and feed preparation, execution of experiments for upstream biologics process development, routine daily maintenance of upstream equipment, and experiment data management and analysis. Organizational skills, communication skills, and recordkeeping are critical to this role.
Responsibilities
- CHO mammalian cell cultures in shaker flasks, WAVE bioreactors, and benchtop bioreactors
- Media and feed formulation as needed for experiments
- Data management and analysis including metabolite, gas, cell count, and titer data
- Media and feed studies to support process development on early phase programs
- Scale-down modeling and range finding to support development and program technology transfers
- Depth filtration filter loading studies to develop cell culture harvest strategies
- Routine maintenance on upstream equipment to maintain daily functionality
Qualifications
- Familiar with aseptic technique methods
- Familiar with experiment design
- Familiar with Microsoft Office, especially Microsoft Excel
- Technical and scientific writing and presentation skills
- Currently enrolled in a chemical engineering, bioengineering, molecular biology or related program to earn a Bachelor of Science degree or equivalent
Skills
- Mammalian cell culture (Preferred)
- Media and buffer preparation (Preferred)
- Understanding of basic engineering and biology concepts (Preferred)
Education
- Currently enrolled in a chemical engineering, bioengineering, molecular biology or related program to earn a Bachelor of Science degree or equivalent