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Sr. Software Engineer/Tech Lead, Data & AI Engineering

Natera
September 30, 2026
Full-time
Remote
Worldwide
IT
Role: Senior Data & AI Engineering Tech Lead at Natera, responsible for defining and implementing the technical strategy for analytics and AI solutions supporting business stakeholders in a regulated genetic testing environment. Responsibilities include owning architecture, translating stakeholder needs into technical designs, building scalable data pipelines, developing data models and semantic layers, and deploying AI-powered workflows using agentic tools and LLM frameworks. The role emphasizes engineering leadership, hands-on solution development, establishing engineering standards, and ensuring data quality, lineage, privacy, and compliance with regulations like HIPAA and CLIA. The position entails mentoring engineers, promoting AI-native development practices, and collaborating with cross-functional teams, including data platform and AI platform groups, to leverage shared foundations. The candidate must have 7+ years of experience in data or software engineering, with 2+ years leading technical design and delivery, proficiency in SQL and Python, expertise with cloud data warehouses (Snowflake/AWS), and experience with transformation frameworks (dbt, Airflow). Knowledge of LLM frameworks (LangChain, Bedrock), data modeling, and data governance is essential. Preferred qualifications include experience in healthcare or regulated domains handling PHI, lab data systems, and BI tools like Looker or Tableau. The role is remote in the USA, with compensation ranging from $150,400 to $188,000. This senior, hands-on position offers the opportunity to influence data and AI systems in a pioneering cell-free DNA testing leader, contributing to innovative healthcare solutions.