Sr. Manager, Screening & Compound Management

Role Summary

The Senior Manager, Screening and Compound Management is integral to optimizing high-throughput screening robotic platforms and compound operations, directly supporting drug discovery initiatives. This role ensures the execution of high-quality biochemical and cell-based assays, overseeing vital processes such as compound handling, storage, and screening. By safeguarding the integrity of compound libraries and streamlining workflows, the senior manager accelerates research timelines and delivers essential data for early-stage drug development. Leading a multidisciplinary team, the senior manager fosters a collaborative environment that champions innovation and continuous improvement through the adoption of advanced technologies like automated liquid handling systems and data analytics tools. In addition to technical responsibilities, the senior manager engages in strategic planning and resource allocation to address dynamic stakeholder needs, aligning compound management strategies with broader research goals, prioritizing screening campaigns, acquiring new chemical entities, and collaborating with teams in medicinal chemistry, biology, and informatics to ensure adaptability in a fast-paced research environment.

Responsibilities

• Lead the strategic planning and execution of high-throughput screening campaigns, ensuring that all activities align with organizational goals and project timelines.
• Leading cross-functional teams to design robust screening workflows, optimize assay conditions, and leading the implementation of cutting-edge technologies to enhance data quality and research throughput.
• Lead lab staff to anticipate challenges, troubleshoot technical issues, and adapt strategies critical to maintaining the efficiency and reliability of screening operations.
• Provide detailed reports and analyses of screening outcomes, ensuring that findings are effectively communicated to stakeholders and integrated into broader research initiatives.
• Oversees the management strategy of the compound library, a cornerstone of the organization‚Äôs research and development efforts.
• Leads the implementation of advanced inventory management systems and establishment and supervision of rigorous quality control protocols.
• Work closely with medicinal chemistry teams to expand the library with diverse and high-value compounds while maintaining compliance with regulatory and safety standards.
• Leads the team in the development of strategies to optimize compound storage conditions and ensure long-term stability, safeguarding the organization‚Äôs investment in its chemical assets.
• Leads a multidisciplinary team of scientists and technicians, providing mentorship, performance feedback, and opportunities for professional growth.
• Leads continuous improvement initiatives to enhance the efficiency and impact of screening and compound management processes.
• Establishes key performance indicators (KPIs) to measure the effectiveness of processes and identify areas for optimization, ensuring that all initiatives are aligned with the organization‚Äôs strategic objectives.

Qualifications

• Required: Bachelor‚Äôs degree in chemistry, biology, biochemistry, or a related field with a minimum of 8 years of experience in compound management, high-throughput screening, or a related area within the pharmaceutical or biotechnology industry.
• Preferred: Significant automation experience or Master‚Äôs degree or Ph.D. in a scientific-related discipline.
• Required: Hands-on experience in managing compound libraries, designing screening workflows, and utilizing automation technologies.
• Required: Competency in at least one programming language (e.g., C++, Visual Basic, Python, JavaScript, Java).
• Required: Proficiency in laboratory automation systems, liquid handling platforms, and data management tools.
• Required: Familiarity with software systems such as LIMS and cheminformatics platforms.
• Required: Ability to troubleshoot technical challenges in a dynamic research environment.
• Preferred: Strategic mindset and a commitment to driving continuous improvement; ability to identify emerging trends in screening technologies and compound management.
• Preferred: Proactive problem-solving and a focus on operational excellence; balancing technical expertise with strategic vision.

Education

• Bachelor‚Äôs degree in chemistry, biology, biochemistry, or a related field.

Additional Requirements

• Travel: Limited travel between PTC facilities in New Jersey