Sr. Director, Portfolio Strategy and Analytics | Onsite San Diego HQ
Neurocrine Biosciences
September 02, 2026
Remote friendly (San Diego, CA)
United States
Corporate Functions
Responsibilities:
- Lead enterprise portfolio strategy, optimization, analytics, and resource planning across R&D.
- Advise executive leadership with data-driven insights for portfolio prioritization, investment, resource allocation, and long-range planning.
- Develop and implement portfolio optimization frameworks, forecasting models, scenario analyses, and decision-support capabilities.
- Own/manage multi-year compound flow models (risk-adjusted/non-risk-adjusted) and transition probability models across stages/modalities.
- Lead executive portfolio prioritization/trade-off discussions and evaluate risks/opportunities to maximize portfolio value.
- Design quantitative models for forecasting, probability of success, timelines, and investment decisions; perform add/remove/accelerate/delay/restructure scenario analysis.
- Lead enterprise resource planning and capacity forecasting; align portfolio objectives with capacity, budget, and long-range assumptions.
- Own portfolio planning systems (e.g., Planisware), establish data standards/governance/analytics best practices, and drive continuous improvement.
- Build executive dashboards/reviews and provide analytical support for business development and strategic investments.
Requirements:
- BS/BA + 14+ years, or MS + 12+ years, or advanced degree (PhD/PharmD/MBA) + 10+ years in relevant industry.
- Deep knowledge of pharma development lifecycle; strong portfolio strategy/forecasting/probability-of-success/scenario planning and governance.
- Advanced Planisware or comparable platforms; experience implementing/optimizing portfolio analytics and governance.
- Strong analytical, strategic, and executive-communication skills; ability to lead via influence in matrixed organizations; ability to mentor.
Benefits/Compensation (as stated):
- Annual base salary: $226,500–$309,000; annual bonus target 35%; equity long-term incentive eligibility; retirement match, paid time off/leave, and medical/dental/vision coverage.
- Lead enterprise portfolio strategy, optimization, analytics, and resource planning across R&D.
- Advise executive leadership with data-driven insights for portfolio prioritization, investment, resource allocation, and long-range planning.
- Develop and implement portfolio optimization frameworks, forecasting models, scenario analyses, and decision-support capabilities.
- Own/manage multi-year compound flow models (risk-adjusted/non-risk-adjusted) and transition probability models across stages/modalities.
- Lead executive portfolio prioritization/trade-off discussions and evaluate risks/opportunities to maximize portfolio value.
- Design quantitative models for forecasting, probability of success, timelines, and investment decisions; perform add/remove/accelerate/delay/restructure scenario analysis.
- Lead enterprise resource planning and capacity forecasting; align portfolio objectives with capacity, budget, and long-range assumptions.
- Own portfolio planning systems (e.g., Planisware), establish data standards/governance/analytics best practices, and drive continuous improvement.
- Build executive dashboards/reviews and provide analytical support for business development and strategic investments.
Requirements:
- BS/BA + 14+ years, or MS + 12+ years, or advanced degree (PhD/PharmD/MBA) + 10+ years in relevant industry.
- Deep knowledge of pharma development lifecycle; strong portfolio strategy/forecasting/probability-of-success/scenario planning and governance.
- Advanced Planisware or comparable platforms; experience implementing/optimizing portfolio analytics and governance.
- Strong analytical, strategic, and executive-communication skills; ability to lead via influence in matrixed organizations; ability to mentor.
Benefits/Compensation (as stated):
- Annual base salary: $226,500–$309,000; annual bonus target 35%; equity long-term incentive eligibility; retirement match, paid time off/leave, and medical/dental/vision coverage.