Prime Medicine, Inc. logo

Spring 2026 Co-op: CAR-T Immunology

Prime Medicine, Inc.
On-site
Cambridge, MA
Clinical Research and Development

Role Summary

Spring 2026 co-op position on the Immunology team, focusing on screening and validation of Prime Editing strategies in immune-related indications. Work with human immune cells to support CAR-T immunology projects and gene editing studies. Ideal for a candidate pursuing cell and molecular biology with interest in translating research toward potential therapeutics.

Responsibilities

  • Cell Culture & Functional Assays
    • Perform primary human cell culture using aseptic technique
    • Conduct program-specific cell-based functional assays, including flow cytometry
    • Process in vivo samples for downstream analysis
  • Molecular Biology & Gene Editing
    • Extract genomic DNA, perform digital PCR (dPCR), and prepare samples for next-generation DNA sequencing
    • Assist in Prime Editing experiments and downstream molecular analysis
  • Data Analysis & Collaboration
    • Design and plan experiments with scientific rigor
    • Analyze and interpret data, contributing to team discussions
    • Document results in an ELN, and present findings in team meetings

Qualifications

  • Required: B.S. candidate in Cell & Molecular Biology or a related major
  • Required: Basic understanding of cell and molecular biology
  • Required: Strong teamwork and communication skills
  • Required: Scientific curiosity, attention to detail, and excellent record-keeping skills
  • Required: Passionate about human disease research and motivated to help patients
  • Preferred: Hands-on experience with aseptic technique and cell culture
  • Preferred: Experience with basic molecular biology techniques (e.g., DNA extraction, PCR)
  • Preferred: Familiarity with flow cytometry or other immune-based assays