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Senior Scientist I/II, Pharmacology and Translational Science

Artiva Biotherapeutics
September 03, 2026
Remote friendly (San Diego, CA)
United States
Clinical Research and Development
Job Summary:
Artiva Biotherapeutics seeks a Senior Scientist I/II responsible for translational assay oversight and data analysis supporting ongoing clinical trials. The role focuses on identifying pharmacodynamic and predictive biomarkers for NK cell-mediated clinical response in autoimmunity.

Key Responsibilities:
- Perform translational research related to autoimmune diseases.
- Develop and conduct cell-based assays: immunophenotyping, cytotoxicity, immune cell proliferation, and serum cytokine/chemokine analysis.
- Perform QC of flow cytometry data (panel QC, staining/compensation controls, assay performance metrics).
- Support clinical biospecimen characterization, data analysis, and reporting (presentations and written reports) for clinical trials.
- Present findings at scientific conferences and contribute to peer-reviewed manuscript preparation.
- Support clinical trial activities end-to-end by partnering with Clinical Operations and Clinical Development on biomarker strategy, sample logistics, and interpretation of clinical data.
- Process human clinical samples for biomarker analysis.
- Ensure compliance with protocols/SOPs and standard laboratory procedures (notebook documentation and safety protocols).

Requirements:
- PhD in immunology/life sciences (5+ years; 6–7 years for Level II) or MS (10+ years) in biotech/pharma; prior translational clinical-trials experience preferred.
- Expertise in multi-parameter flow cytometry (panel design, acquisition, analysis, QC) and functional immune assays (e.g., proliferation, cytokine production, cytotoxicity).
- Strong human immunology background; B-cell immunology/bio desirable; autoimmunity experience preferred.
- Translational science experience with direct clinical trial involvement (biomarker sample analysis, clinical reporting, cross-functional collaboration, data management) strongly preferred.
- Strong understanding of drug development.
- Excellent communication, teamwork, attention to detail, and data quality.
- Computer skills with FlowJo, OMIQ, GraphPad Prism, and Microsoft Office.

Benefits (explicitly listed):
- Medical, Dental, Vision; Group Life Insurance; Long Term Disability (LTD); 401(k); EAP; FSA; PTO; company-paid holidays.
- Bonus.ly recognition program.

Base Salary:
- $149,000–$183,000 annually (varies by level, skills, experience).