Senior Scientist - Functional Genomics

Role Summary

Senior Scientist - Functional Genomics

Responsibilities

• Conduct impactful high throughput screening and profiling approaches for target discovery
• Help identify and implement new technologies to accelerate discovery
• Develop and execute downstream mechanistic assays to validate and advance targets
• Collaborate closely with disease area, human genetics, computational biology, and therapeutic development teams to make actionable decisions as a technical and intellectual subject matter expert
• Present research findings to cross-functional groups at internal and external meetings and publish scientific findings in peer-reviewed forums

Qualifications

• Basic Qualifications:
  • Doctorate degree PhD OR PharmD OR MD [and relevant post-doc where applicable]
  • Or Master’s degree and 3 years of directly related experience
  • Or Bachelor’s degree and 5 years of directly related experience
• Preferred Qualifications:
  • Doctorate degree in genetics, genomics, cell and molecular biology, systems biology, or related disciplines
  • Demonstrated track record of independent critical thinking, complex problem solving, and innovative research, evidenced by significant contributions to discovery programs and publications in top tier journals
  • Hands-on expertise conducting and delivering complex screening campaigns for discovery
  • Proficiency with experimental design, data generation, and analysis principles across a broad range of technologies and assays including transcriptomics, imaging, and cytometry
  • Expertise with molecular and cell biology tools such as CRISPR, overexpression constructs, lentivirus, and various approaches for cell engineering
  • Strong expertise with genomic assays
  • Strong expertise on prosecuting insights from human genetics along with approaches for in depth biological study of potential targets
  • Experience with programming (e.g. in R/Python), Unix/Linux environments, and cloud computing environments for the analysis of large omics datasets is preferred
  • Strong written, verbal, and oral communication skills and ability to thrive in cross-functional settings

Skills

• Omics technologies and cellular profiling
• Target discovery and validation
• Data analysis and interpretation of large omics datasets
• Collaborative cross-functional communication

Education

• Doctorate degree (PhD) or equivalent in relevant field preferred

Additional Requirements

• None provided beyond qualifications and responsibilities