Senior Medical Director, Multi-Cancer Early Detection (MCED)

Position Summary
- The Senior Medical Director for Multi-Cancer Early Detection (MCED) will guide the medical, scientific, and clinical strategy for Caris’ MCED portfolio.

Job Responsibilities
- Provide medical, scientific, and clinical expertise for MCED strategy, clinical protocols, regulatory submissions, and study design.
- Serve as the principal internal medical authority for MCED programs, ensuring scientific rigor and alignment with corporate objectives.
- Interpret and communicate clinical and analytical performance data (safety, efficacy, and real-world evidence).
- Oversee development of scientific publications, abstracts, peer-reviewed manuscripts, and presentations.
- Partner cross-functionally with Regulatory, Clinical Operations, Biostatistics, R&D, Product, Market Access, and Commercial to ensure program execution and clinical relevance.
- Engage and cultivate relationships with external experts, investigators, clinical partners, advocacy groups, and regulatory agencies.
- Lead physician representation of clinical user experience and real-world clinical workflows for MCED products.
- Represent Caris at national/international scientific meetings, advisory boards, and industry forums.
- Monitor emerging trends in oncology, early detection, liquid biopsy, genomics, biomarkers, and relevant clinical practice guidelines.

Required Qualifications
- MD (or equivalent) with board certification in oncology, hematology, clinical pathology, or related specialty.
- ≥5 years direct patient care experience (ideally oncology; exposure to cancer screening/diagnostic pathways).
- ≥5 years clinical/product development experience (ideally oncology diagnostics, screening, or early detection).
- Expertise in biomarker-driven oncology, molecular diagnostics, cancer screening methodologies, or liquid biopsy platforms.
- Strong understanding of clinical trial design, evidence generation, and regulatory considerations for diagnostic products.
- Outstanding written/verbal communication; experience presenting to scientific/clinical/executive audiences.
- Proven ability to lead in a fast-paced, matrixed environment while managing multiple priorities.
- Familiarity with health economics, outcomes research, and real-world evidence generation.

Preferred Qualifications
- Experience interacting with regulatory authorities (e.g., FDA, EMA) with contributions to submissions for diagnostic/screening technologies.
- Prior industry leadership experience in diagnostics/biotech/medtech focused on oncology or early detection.
- Established network among oncology KOLs, screening experts, pathology leaders, and/or clinical investigators.

Benefits (if applicable)
- Medical, dental, and vision coverage; Health Savings Account; Flexible Spending Account
- Paid time off (vacation, sick time, holidays)
- 401(k) match and financial planning tools; LTD/STD and voluntary benefits
- Employee Assistance Program; Pet Insurance; Legal Assistance; Tuition Assistance

Application Instructions
- Pre-employment process includes criminal background check, drug screening, credit check (for certain positions), and reference verification.