Alnylam Pharmaceuticals logo

Senior Manager, People Experience

Alnylam Pharmaceuticals
June 26, 2026
Remote friendly (Cambridge, MA)
United States
Human Resources
Key Responsibilities:
- Serve as a trusted People Experience Partner to leaders across Expertise Areas; coach managers to strengthen leadership capability, team effectiveness, and performance in alignment with company values and culture.
- Advise and coach managers on performance issues, including development plans and Performance Improvement Plans (PIPs), ensuring timely, fair, and well-documented outcomes.
- Own end-to-end case management for assigned matters (documentation, escalation, resolution) using ServiceNow to ensure accurate and consistent people processes.
- Lead employee relations and disciplinary matters with discretion, empathy, and rigor; ensure consistent application of policies, employment law, and best practices.
- Partner with Employee Relations, Legal, HR Business Partners, and HR Capability on investigations, involuntary separations, reductions in force, and other high-risk/sensitive situations.
- Provide guidance on absence management, leaves of absence, and workplace accommodations.
- Identify trends, root causes, and insights across cases; recommend actions to strengthen culture, leadership effectiveness, and employee experience.
- Support enterprise performance and compensation cycles by coaching managers and reinforcing consistent execution.

Qualifications:
- 5-10 years Human Resources experience required.
- Preferred: HR Generalist experience, Employee Relations, and Performance Management.
- Strong knowledge of employment law and HR best practices.
- Proven ability to manage complex employee situations with discretion and neutrality.
- Exceptional communication and influencing skills; experience coaching/developing managers.
- High emotional intelligence and sound judgment; empathetic yet disciplined decision-making.
- Ability to work in a disciplined environment with data integrity and high-quality case management.
- Experience leveraging case management systems (ServiceNow a plus) and analyzing data trends for continuous improvement.

Benefits (as stated): comprehensive medical/dental/vision; life and disability insurance; lifestyle reimbursement; flexible spending & health savings accounts; 401(k) with generous company match; paid time off, wellness days, holidays, and two recharge breaks; family resources and leave.

Work location: Hybrid; primarily Cambridge, MA.