Senior Manager, Payroll and Equity
Disc Medicine
August 25, 2026
Remote friendly (Watertown, MA)
United States
Human Resources
Position Overview:
Senior Manager, Payroll and Equity will ensure accurate, timely, and compliant processing for all payroll and equity cycles (semi-monthly payrolls, off-cycle payrolls, equity grants, RSU vesting, ESPP purchases, and stock option exercises), including annual processes such as bonus payments and year-end reporting. Partners closely with HR, Finance, Legal, and external auditors/consultants.
Responsibilities:
Payroll
- Process and validate semi-monthly payrolls in ADP Workforce Now with SOX-compliant documentation
- Support equity-related payroll processing (RSU vesting, option exercises, ESPP transactions)
- Collaborate with HR on onboarding/offboarding and employee compensation maintenance
- Maintain payroll system accuracy (earnings codes, deductions, tax configurations, pay rules)
- Manage year-end processing/W-2 reporting; 401(k), payroll tax, and payroll audit/compliance activities
- Manage 401(k) uploads
- Ensure compliance with federal/state/local laws and company policies; review payroll/tax changes and recommend actions
- Manage multi-state processing/reporting (registrations, withholding, unemployment accounts)
- Perform monthly payroll reconciliations, journal entries, bonus accruals; resolve discrepancies
- Generate/analyze payroll reports in ADP Workforce Now; process Concur expense reports
- Communicate clearly with employees on payroll and equity questions
Equity
- Manage Shareworks day-to-day; review ADP-to-Shareworks feeds (demographics/taxes)
- Oversee quarterly RSU vesting; process ESPP changes and semi-annual open enrollment/purchases
- Upload stock grants monthly; prepare annual Form 3921/3922
- Support accounting reporting needs and SOX documentation; support internal/external audit testing for stock compensation
Requirements:
- Bachelor’s degree in Accounting/Finance/HR/Business Administration or related field
- 7–10+ years hands-on multi-state payroll processing (high-growth preferred)
- ADP Workforce Now experience
- 2+ years equity administration for stock options and RSU programs
- Excel proficiency (Pivot Tables, XLOOKUP/VLOOKUP, analysis, reconciliations, reporting) and strong Microsoft Office skills
- Strong analytical/organizational/communication/problem-solving; high attention to detail
- Ability to meet multiple concurrent deadlines; discretion with confidential information
- Ability to work independently and collaboratively in a fast-paced environment
- Experience with complex tax scenarios
- Experience supporting SOX, financial/compliance audits, and 401(k) plans
Preferred:
- Shareworks and NetSuite experience
- Biotech/pharma/life sciences experience
- CPP and/or CEP certification
Application:
Submit your resume to be considered for current and future opportunities.
Senior Manager, Payroll and Equity will ensure accurate, timely, and compliant processing for all payroll and equity cycles (semi-monthly payrolls, off-cycle payrolls, equity grants, RSU vesting, ESPP purchases, and stock option exercises), including annual processes such as bonus payments and year-end reporting. Partners closely with HR, Finance, Legal, and external auditors/consultants.
Responsibilities:
Payroll
- Process and validate semi-monthly payrolls in ADP Workforce Now with SOX-compliant documentation
- Support equity-related payroll processing (RSU vesting, option exercises, ESPP transactions)
- Collaborate with HR on onboarding/offboarding and employee compensation maintenance
- Maintain payroll system accuracy (earnings codes, deductions, tax configurations, pay rules)
- Manage year-end processing/W-2 reporting; 401(k), payroll tax, and payroll audit/compliance activities
- Manage 401(k) uploads
- Ensure compliance with federal/state/local laws and company policies; review payroll/tax changes and recommend actions
- Manage multi-state processing/reporting (registrations, withholding, unemployment accounts)
- Perform monthly payroll reconciliations, journal entries, bonus accruals; resolve discrepancies
- Generate/analyze payroll reports in ADP Workforce Now; process Concur expense reports
- Communicate clearly with employees on payroll and equity questions
Equity
- Manage Shareworks day-to-day; review ADP-to-Shareworks feeds (demographics/taxes)
- Oversee quarterly RSU vesting; process ESPP changes and semi-annual open enrollment/purchases
- Upload stock grants monthly; prepare annual Form 3921/3922
- Support accounting reporting needs and SOX documentation; support internal/external audit testing for stock compensation
Requirements:
- Bachelor’s degree in Accounting/Finance/HR/Business Administration or related field
- 7–10+ years hands-on multi-state payroll processing (high-growth preferred)
- ADP Workforce Now experience
- 2+ years equity administration for stock options and RSU programs
- Excel proficiency (Pivot Tables, XLOOKUP/VLOOKUP, analysis, reconciliations, reporting) and strong Microsoft Office skills
- Strong analytical/organizational/communication/problem-solving; high attention to detail
- Ability to meet multiple concurrent deadlines; discretion with confidential information
- Ability to work independently and collaboratively in a fast-paced environment
- Experience with complex tax scenarios
- Experience supporting SOX, financial/compliance audits, and 401(k) plans
Preferred:
- Shareworks and NetSuite experience
- Biotech/pharma/life sciences experience
- CPP and/or CEP certification
Application:
Submit your resume to be considered for current and future opportunities.