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Senior Manager - HR Business Partner

Caris Life Sciences
June 30, 2026
Remote friendly (Phoenix, AZ)
United States
Human Resources
Position Summary
Senior Manager, HR Business Partner supports commercial, clinical, or corporate functions by translating enterprise HR strategy into business-aligned execution focused on employee relations, talent processes, and organizational effectiveness.

Job Responsibilities
- Primary HR partner to Director/Senior Director leaders within assigned functions.
- May supervise HR team/HRBP associates (coaching, performance management, development).
- Execute HR strategies/programs supporting business objectives, workforce needs, and employee engagement.
- Provide employee relations support: investigations, conflict resolution, performance management guidance.
- Coach managers on performance management, feedback, team effectiveness, and employee development.
- Support talent processes: performance reviews, talent calibration, succession planning.
- Partner on workforce planning: headcount management and organizational changes.
- Support organizational design changes (restructures, role clarity).
- Partner with Total Rewards on compensation programs (including commercial incentive plans).
- Support rollout of HR programs (engagement surveys, performance management cycles, compensation reviews).
- Collaborate with HR Centers of Excellence (Talent Acquisition, Total Rewards, Learning & Development).
- Use HR data/dashboards to monitor trends and provide insights.

Required Qualifications
- Bachelor’s degree (HR, Business Administration, or related).
- 8+ years progressive HR experience (HRBP/generalist); 5+ years in an HR supervisory role.
- Experience supporting fast-paced functions (commercial/sales/clinical).
- Employee relations, performance management, manager coaching experience.
- Strong interpersonal/communication/problem-solving skills.
- Microsoft Office (Word/Excel/Outlook) and internet use.

Preferred Qualifications
- Life sciences/healthcare diagnostics/biotech experience; support for geographically dispersed/field teams.
- SHRM-CP/PHR; Workday or similar HRIS.

Other / Conditions
- Periodic travel; occasional work outside standard hours.
- Pre-employment process includes criminal background check, drug screening, credit check (certain roles), and reference verification.