Senior Manager, CGT Operations Business Process
Vertex Pharmaceuticals
July 01, 2026
Remote friendly (Boston, MA)
United States
Operations
Position Summary
We are seeking a Senior Manager, CGT Operations Business Process to lead global business process initiatives for CASGEVY, collaborating cross-functionally to design and own the end-to-end (vein-to-vein) process in a GxP-regulated environment.
Key Responsibilities
- Lead the evolution of the Global end-to-end (E2E) process by identifying and addressing improvement areas and process gaps with stakeholders across commercial, quality, systems, and manufacturing; spearhead workstreams to implement changes that increase efficiency and support strategic priorities.
- Own and evolve global documentation used across markets and functions, including business process maps, standard operating procedures, and other GxP materials.
- Manage cross-functional forums to advance initiatives, gather insights, and resolve operational challenges; drive scalability through simplification, clarity, and standardization.
- Lead global commercial GxP change management, assessing impact of process updates with subject matter experts and owning change control activities while ensuring quality compliance.
- Advance strategic projects with the Disease Strategy Team (e.g., multi-year scaling roadmap and next-generation manufacturing strategy business process).
Qualifications And Experience
- Proven ability to manage multiple priorities in a fast-paced environment.
- Independent thinker with strong attention to detail and a collaborative mindset.
- Excellent project management skills for complex workstreams with multiple stakeholders across functions.
- Strong meeting facilitation and written and verbal communication skills.
- GxP process and change management experience highly preferred.
- Process analytics and reporting tools familiarity a plus.
How to Apply
Submit your resume and cover letter through the careers portal.
We are seeking a Senior Manager, CGT Operations Business Process to lead global business process initiatives for CASGEVY, collaborating cross-functionally to design and own the end-to-end (vein-to-vein) process in a GxP-regulated environment.
Key Responsibilities
- Lead the evolution of the Global end-to-end (E2E) process by identifying and addressing improvement areas and process gaps with stakeholders across commercial, quality, systems, and manufacturing; spearhead workstreams to implement changes that increase efficiency and support strategic priorities.
- Own and evolve global documentation used across markets and functions, including business process maps, standard operating procedures, and other GxP materials.
- Manage cross-functional forums to advance initiatives, gather insights, and resolve operational challenges; drive scalability through simplification, clarity, and standardization.
- Lead global commercial GxP change management, assessing impact of process updates with subject matter experts and owning change control activities while ensuring quality compliance.
- Advance strategic projects with the Disease Strategy Team (e.g., multi-year scaling roadmap and next-generation manufacturing strategy business process).
Qualifications And Experience
- Proven ability to manage multiple priorities in a fast-paced environment.
- Independent thinker with strong attention to detail and a collaborative mindset.
- Excellent project management skills for complex workstreams with multiple stakeholders across functions.
- Strong meeting facilitation and written and verbal communication skills.
- GxP process and change management experience highly preferred.
- Process analytics and reporting tools familiarity a plus.
How to Apply
Submit your resume and cover letter through the careers portal.