Senior IT Systems Engineer
10x Genomics
September 23, 2026
Full-time
Remote friendly (Pleasanton, CA)
Worldwide
IT
Role: Linux Systems Administrator specializing in high-performance computing (HPC) and enterprise storage for biopharma data environments. Objectives: manage scalable, secure HPC infrastructure supporting genomics research with petabyte-scale data, ensuring performance, availability, and data integrity. Responsibilities: design, operate, and document hybrid (on-premises/cloud) compute/storage clusters; oversee data backup, archiving, and replication; enforce data security and lifecycle policies; participate in operational support and incident reviews. Requirements: minimum 5 years managing large-scale HPC or enterprise storage, expertise in Linux distributions (Debian, Ubuntu, Amazon Linux), data protection, and backup technologies; proficiency with AWS (S3, EBS, EC2), file sharing protocols (NFS, SMB), Active Directory/LDAP, scripting (Bash/Python), and IaC tools (Ansible, Terraform). Preferred: familiarity with data classification, encryption, virtualization (VMware, Proxmox), and strong organizational/communication skills. High-Value: supporting genomics research data infrastructure, hybrid cloud environments, and high-performance storage solutions in a biopharma setting. Work setup: not specified; likely hybrid/on-site given infrastructure scope.