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Senior IT Systems Administrator

Cabaletta Bio
4 hours ago
Remote friendly (Philadelphia, PA)
United States
IT
Responsibilities:
- Own and contribute to the design, implementation, configuration, and support of servers, network devices, and firewalls in collaboration with IT and business teams
- Own operational health of IT systems: end-user support, break-fix, monitoring, patch management, backup/recovery, administration, troubleshooting, and issue resolution
- Lead and coordinate Tier 2/3 escalations to ensure timely resolution
- Serve as primary technical point of contact for external service providers; ensure alignment with operational and security expectations
- Partner with external support providers to ensure consistent service delivery and adherence to service expectations
- Review escalations, recurring issues, and incident trends to identify improvement opportunities and reduce operational risk
- Coordinate and communicate infrastructure/system changes to ensure documentation, awareness, and process alignment
- Collaborate with internal stakeholders and service providers to prioritize work and support a high-quality end-user experience
- Contribute to continuous improvement of IT service delivery processes and operational practices
- Administer/support core Linux and Microsoft technologies across cloud and hybrid environments
- Maintain/support AWS hybrid cloud environments (EC2, VPC, Elastic Load Balancing, RDS, S3)
- Maintain/support Microsoft 365 systems (Exchange, SharePoint, Teams, Entra ID)
- Support implementation/maintenance of cybersecurity controls (identity, access, endpoint protections)
- Support identity and access management (role-based access; least privilege)
- Assist with monitoring/responding/remediating security events
- Support vulnerability management (patching, hardening, periodic security reviews)
- Maintain business continuity and disaster recovery systems; perform periodic testing
- Ensure compliance with cybersecurity and regulatory standards (audits, risk assessments, remediation)
- Create/maintain comprehensive IT documentation (SOPs, user guides, training materials, test/validation docs)
- Support lifecycle management across on-prem and cloud
- Collaborate with QA/CSV teams to support validation (test script development/execution)
- Support data integrity processes for IT systems and laboratory environments
- Support staff/partners with technology use; provide training as required
- Other assignments/projects as required

Qualifications:
- Bachelor’s degree with 5+ years systems administration experience in biotech/pharma/life sciences
- Experience with LAN/WAN, including wireless and firewall management
- Experience with segmented/regulated network environments (plus)
- Strong AWS experience: EC2, VPC, Elastic Load Balancing, RDS, S3
- Strong Windows Server (2016/2019/2022) and RHEL (7/8/9)
- Microsoft 365 experience: Exchange, SharePoint, Teams, Entra ID (SSO, SAML, OIDC)
- Knowledge of Active Directory, Group Policy, and file system permissions
- Experience with backup/recovery platforms
- Cybersecurity experience in regulated environments (patching, access controls, endpoint security)
- Familiarity with firewalls, network security concepts, and identity management
- Exposure to security monitoring tools (SIEM, EDR) (plus)
- Experience with external service providers/managed services environments (preferred)
- Excellent problem-solving, communication, and organizational skills
- Strong curiosity and ability to learn quickly in a fast-paced environment
- Client support orientation; ability to work with users across technical skill levels
- Comfortable in a growing, dynamic organization

Benefits (as stated): competitive benefits, PTO, and stock option plans