Senior IT Support Engineer
uniQure
August 12, 2026
Remote friendly (Lexington, MA)
United States
IT
Responsibilities:
- Administer and support Microsoft 365 (Exchange Online, SharePoint Online, OneDrive), including licensing and end-user support.
- Administer Entra ID identity and access management: user/group lifecycle, role/access assignment, conditional access and MFA policies, and access reviews.
- Own Microsoft Teams support for Lexington, including Teams calling, meeting rooms, collaboration governance, and troubleshooting.
- Co-own and direct global standards for onboarding (account/access/device provisioning) and maintain standards in Intune (enrollment, configuration profiles, compliance policies, application deployment).
- Act as senior technical escalation point for Lexington IT support; set technical standards and guide support engineers.
- Coordinate security and infrastructure matters with the Sr. Cyber Security Engineer and Sr. System Engineer.
- Resolve IT incidents/requests via the ticket system; ensure timely, prioritized handling.
- Provide helpdesk support across a mixed macOS/Windows device environment, plus mobile telephony and meeting-room/video conferencing equipment; support remote/field users.
- Perform application and user management for assigned applications; act as backup Application Manager for specified systems; maintain work instructions.
- Ensure IT compliance with relevant regulatory/quality requirements; participate in internal/external audits.
- Perform identity/endpoint/application security tasks and software updates aligned with change control.
- Maintain asset and knowledge inventory.
Qualifications & Skills:
- Hands-on experience with Microsoft 365, Entra ID, and Microsoft Teams (including Teams calling) in an international enterprise environment.
- College or ICT/equivalent grade in Computer Sciences.
- Working experience and/or certifications.
- 8+ years in technology services (Support Engineer/Service Administrator or equivalent) using ITIL-based practices; ITIL certification advantage.
- Strong hands-on Intune experience (enrollment, config profiles, compliance policies, app deployment).
- Strong macOS support plus solid Windows client support; Intune management of both platforms is advantageous.
- Ability to support remote/field users effectively (remote troubleshooting, device management, clear guidance).
- Strong communication (written/verbal) and broad technology knowledge.
- Experience in commercial and preferably multi-cultural international organizations.
- Physically able to manage/support workplaces.
- Administer and support Microsoft 365 (Exchange Online, SharePoint Online, OneDrive), including licensing and end-user support.
- Administer Entra ID identity and access management: user/group lifecycle, role/access assignment, conditional access and MFA policies, and access reviews.
- Own Microsoft Teams support for Lexington, including Teams calling, meeting rooms, collaboration governance, and troubleshooting.
- Co-own and direct global standards for onboarding (account/access/device provisioning) and maintain standards in Intune (enrollment, configuration profiles, compliance policies, application deployment).
- Act as senior technical escalation point for Lexington IT support; set technical standards and guide support engineers.
- Coordinate security and infrastructure matters with the Sr. Cyber Security Engineer and Sr. System Engineer.
- Resolve IT incidents/requests via the ticket system; ensure timely, prioritized handling.
- Provide helpdesk support across a mixed macOS/Windows device environment, plus mobile telephony and meeting-room/video conferencing equipment; support remote/field users.
- Perform application and user management for assigned applications; act as backup Application Manager for specified systems; maintain work instructions.
- Ensure IT compliance with relevant regulatory/quality requirements; participate in internal/external audits.
- Perform identity/endpoint/application security tasks and software updates aligned with change control.
- Maintain asset and knowledge inventory.
Qualifications & Skills:
- Hands-on experience with Microsoft 365, Entra ID, and Microsoft Teams (including Teams calling) in an international enterprise environment.
- College or ICT/equivalent grade in Computer Sciences.
- Working experience and/or certifications.
- 8+ years in technology services (Support Engineer/Service Administrator or equivalent) using ITIL-based practices; ITIL certification advantage.
- Strong hands-on Intune experience (enrollment, config profiles, compliance policies, app deployment).
- Strong macOS support plus solid Windows client support; Intune management of both platforms is advantageous.
- Ability to support remote/field users effectively (remote troubleshooting, device management, clear guidance).
- Strong communication (written/verbal) and broad technology knowledge.
- Experience in commercial and preferably multi-cultural international organizations.
- Physically able to manage/support workplaces.