Senior Engineer: Mathematical Modeling and Simulation

Role Summary

Senior Engineer: Mathematical Modeling and Simulation is a technical role in Amgen’s Combination Product Operations Digital and Data Strategies group. You will develop and apply physics-based and empirical models (including finite element models) of drug delivery devices to improve understanding, robustness, monitoring, and decision-making across the product lifecycle. You will own in-silico modeling projects, collaborate across multi-functional teams, and mentor other simulation experts.

Responsibilities

• Implement explicit and implicit FEM structural models with appropriate simplifications to efficiently represent the physical system.
• Apply engineering principles (kinematic, structural, tolerance analysis) with material characterization and testing to create in-silico models capturing device behavior during use, assembly, and transport.
• Continuously improve in-silico models, manage model lifecycle, and enhance methods to ensure efficiency and trustworthiness.
• Explore new opportunities in in-silico and data-driven computational models; model real-world scenarios with appropriate detail to inform decision-making in reduced time.
• Simulate complaints and real-world issues within the lifecycle of combination products; develop models that support root cause analysis.
• Provide leadership and deliver work in a fast-paced, multi-project, cross-functional environment; deliver predictions and insights on time to solve production and customer problems.
• Own model backlog, communicate modelling scope and limitations to stakeholders, and mentor other simulation experts in using simulation technologies.

Qualifications

• Basic Qualifications:
  • Doctorate degree
  • OR Master‚Äôs degree and 2 years of Engineering experience
  • OR Bachelor‚Äôs degree and 4 years of Engineering experience
  • OR Associate‚Äôs degree and 8 years of Engineering experience
  • OR High school diploma / GED and 10 years of Engineering experience
• Preferred Qualifications:
  • Finite element model experience with SIMULIA, ANSYS, ALTAIR, or COMSOL
  • Experience in explicit FEM modelling and non-linear structural models; contact modelling, large deformations, plasticity, and hyperelasticity
  • Knowledge of statistics and robustness analysis to capture variability in processes and device dimensions
  • Programming in Python and/or MATLAB; scripting with Abaqus user subroutines, Tcl/Tk to automate model creation and post-processing
  • Experience with combination products, regulatory requirements, medical device development, design controls, and process controls
  • Excellent communication, presentation, and technical documentation skills
  • Intellectual curiosity and ability to learn new concepts/frameworks rapidly
  • Ability to manage multiple priorities in a collaborative, cross-functional environment

Education

• As listed under Basic Qualifications: Doctorate; or Master‚Äôs/Bachelor‚Äôs with engineering experience; or Associate‚Äôs with engineering experience; or High school diploma/GED with extensive engineering experience