Senior Director/Vice President Clinical Pharmacology

Role Summary

The Senior Director/Vice President Clinical Pharmacology will build the clinical pharmacology function to enable the design and efficient execution of all Phase 2-3 programs across multiple autoimmune therapeutic areas. The role provides strategic drug development input and clinical pharmacology expertise to cross-functional teams to facilitate the execution of ongoing and future Vor programs. It will require developing strong working relationships within Clinical Development and with key functions including Pharmacovigilance and Drug Safety, Regulatory, Discovery, CMC, Translational, Trial Operations, Biostatistics and Program Management. Some international travel may be required.

Responsibilities

• Build the clinical pharmacology department to support Vor’s pipeline
• Provide strategic and clinical pharmacology leadership to all development programs
• Develop stage-gated and flexible financial and human resource approach to account for evolving requirements for each program
• Develop and implement new clinical pharmacology tools and technologies to drive smarter drug development for programs, where appropriate
• Represent the clinical pharmacology department function and provide subject matter expertise to cross-functional project teams
• Develop and maintain collaborative working relationships with colleagues within and outside the department
• Author/review/approve clinical protocols, analysis plans, study reports and regulatory submissions
• Develop high quality clinical pharmacology plans and content for global regulatory submissions, including INDs, protocols and IBs etc.
• Develop and propose short- and long-term objectives for early clinical development in accordance with overall Company strategies and goals
• Plan and manage budget proposals and approved budgets in accordance with Vor’s strategic and operating plans and Finance policies
• Build out the Clinical pharmacology department as the number of programs increase which includes recruiting, leading, directing, and developing direct reports, in accordance with the Company’s HR policies and practices
• Act in accordance with Company policies, including, for example, the Code of Business Conduct and Ethics and ensure policies are understood and followed by direct reports, if any

Qualifications

• Ph.D. or MD with a minimum of 12+ years of experience in clinical pharmacology roles of increasing leadership and scope in the autoimmune area
• Prior successful experiences in supporting global regulatory interactions, including INDs, EOP1/2, and scientific advice
• Proven experience in leading and managing sophisticated scientific teams
• Excellent communication skills and ability to effectively collaborate with cross-functional teams and influence decision making process
• Hands on experience in design and executing a variety studies
• Appropriate publication records in top-tier and peer-reviewed journals are required to establish credibility with a highly talented scientific team
• Some US and international travel required