Senior Director, Revenue & Government Pricing
Amylyx Pharmaceuticals
August 25, 2026
Remote friendly (Cambridge, MA)
United States
Market Access
Responsibilities:
- Provide strategic leadership and oversight for revenue accounting, gross-to-net operations, government pricing, and related commercial accounting activities to ensure compliance with U.S. GAAP and regulatory requirements.
- Partner with senior leadership to evaluate and inform pricing, contracting, reimbursement, and market access strategies using revenue, gross-to-net, and government pricing insights.
- Lead month-end and quarter-end close for revenue, gross-to-net reserves, accounts receivable, and related balances (journal entries, reconciliations, analyses, controls, management reporting).
- Partner cross-functionally to support forecasting, contracting, product launches, revenue recognition, and gross-to-net planning.
- Own government pricing: oversee methodologies, controls, calculations, validations, and submissions across federal and state pricing programs.
- Serve as business owner for outsourced government pricing provider (service delivery, data integrity, regulatory compliance, SLA performance, issue resolution, audit readiness, continuous improvement).
- Oversee third-party commercial operations (3PL billing, invoicing, cash application, chargebacks, AR).
- Develop revenue and gross-to-net reporting, analytics, and forecasting capabilities.
- Establish and maintain scalable processes, systems, policies, and internal controls for growth, audit readiness, SOX compliance, and evolving regulations.
- Lead internal/external audits and support SEC reporting.
- Build, mentor, and develop the team; advise senior leadership.
- Lead special projects as needed.
Required Qualifications:
- Bachelor’s degree (Accounting, Finance, Business); CPA strongly preferred.
- 15+ years progressive pharma/biotech/life sciences accounting & finance experience, including leadership for revenue accounting, gross-to-net, and government pricing.
- Knowledge of US GAAP, Sarbanes-Oxley controls; SEC reporting support (10-K, 10-Q).
- Experience with government pricing platforms and managing outsourced providers.
- Supervisory experience coaching and developing team members.
- Self-motivated; collaborative and independent.
- Strong communication skills; excellent attention to detail; ability to manage multiple priorities and deadlines.
- Ability to travel occasionally and work non-standard hours.
Preferred Qualifications:
- CPA and/or MBA.
- Experience supporting commercial pharmaceutical product launches (GTN modeling, government pricing readiness).
- NetSuite experience.
Compensation:
- Estimated pay range: $236,000–$266,000 USD.
- Provide strategic leadership and oversight for revenue accounting, gross-to-net operations, government pricing, and related commercial accounting activities to ensure compliance with U.S. GAAP and regulatory requirements.
- Partner with senior leadership to evaluate and inform pricing, contracting, reimbursement, and market access strategies using revenue, gross-to-net, and government pricing insights.
- Lead month-end and quarter-end close for revenue, gross-to-net reserves, accounts receivable, and related balances (journal entries, reconciliations, analyses, controls, management reporting).
- Partner cross-functionally to support forecasting, contracting, product launches, revenue recognition, and gross-to-net planning.
- Own government pricing: oversee methodologies, controls, calculations, validations, and submissions across federal and state pricing programs.
- Serve as business owner for outsourced government pricing provider (service delivery, data integrity, regulatory compliance, SLA performance, issue resolution, audit readiness, continuous improvement).
- Oversee third-party commercial operations (3PL billing, invoicing, cash application, chargebacks, AR).
- Develop revenue and gross-to-net reporting, analytics, and forecasting capabilities.
- Establish and maintain scalable processes, systems, policies, and internal controls for growth, audit readiness, SOX compliance, and evolving regulations.
- Lead internal/external audits and support SEC reporting.
- Build, mentor, and develop the team; advise senior leadership.
- Lead special projects as needed.
Required Qualifications:
- Bachelor’s degree (Accounting, Finance, Business); CPA strongly preferred.
- 15+ years progressive pharma/biotech/life sciences accounting & finance experience, including leadership for revenue accounting, gross-to-net, and government pricing.
- Knowledge of US GAAP, Sarbanes-Oxley controls; SEC reporting support (10-K, 10-Q).
- Experience with government pricing platforms and managing outsourced providers.
- Supervisory experience coaching and developing team members.
- Self-motivated; collaborative and independent.
- Strong communication skills; excellent attention to detail; ability to manage multiple priorities and deadlines.
- Ability to travel occasionally and work non-standard hours.
Preferred Qualifications:
- CPA and/or MBA.
- Experience supporting commercial pharmaceutical product launches (GTN modeling, government pricing readiness).
- NetSuite experience.
Compensation:
- Estimated pay range: $236,000–$266,000 USD.