Senior Director, Medical Affairs

Role Summary

Location: New York, NY (Hybrid). Cellectis is seeking a highly experienced Senior Director, Medical Affairs to shape and operationalize the company’s medical affairs strategy across its clinical-stage portfolio. Reporting to the Chief Medical Officer, this leader will elevate the company’s scientific presence, support pipeline advancement, and ensure medical excellence in evidence generation, scientific communications, and external engagement. This role targets immuno-oncology expertise, strategic agility, and a patient-centered approach to innovation.

Responsibilities

• Partner with the CMO to develop and execute Cellectis’ medical affairs strategy.
• Build and manage critical medical affairs capabilities, including medical strategy, medical communications, publications, and scientific engagement.
• Provide expert scientific and medical insights across immuno-oncology programs.
• Lead engagement with key opinion leaders, investigators, and scientific experts.
• Represent Cellectis at scientific meetings, advisory boards, and congresses.
• Drive creation of scientific platforms and data-driven communication strategies.
• Oversee development of medical information, publications, and internal scientific education.
• Identify and address data gaps through evidence-generation initiatives.
• Support clinical development and early-access programs with medical expertise.
• Integrate patient insights into medical and clinical strategies.
• Partner cross-functionally with clinical development, regulatory and communications affairs to ensure alignment and shared decision-making.
• Establish governance processes, operational metrics, and reporting frameworks.
• Promote a culture of scientific rigor, compliance, and patient focus.

Qualifications

• PharmD or MD experience in hematology/oncology.
• 15+ years of medical affairs and/or clinical development experience in the biopharmaceutical industry.
• Demonstrated experience engaging KOLs, TA experts, payors and patient advocacy organizations.
• Experience in drug development and/or clinical practice; demonstrated knowledge of competitive landscape, trends, and physician practices.
• Skilled at presenting clinical and non-clinical data to external audiences and management teams.
• Clinical development experience highly preferred.

Skills

• Excellent clinical judgment and decision-making skills.
• Strong interpersonal and communication skills, with the ability to influence cross-functional teams.
• Demonstrated ability to build strong partnerships with investigators, KOLs, and internal stakeholders.
• Proven ability to lead cross-functional teams in a matrixed environment.
• Mission-driven leader with a passion for improving patient outcomes.
• Comfortable in a fast-paced, innovative biotech environment.

Additional Requirements

• Ability to travel up to 50-60% of time.