Senior Director, HEOR & Evidence Strategy

Responsibilities:
- Own the Integrated Evidence Generation Plan (IEGP) across programs; align with clinical development, medical affairs, and commercial strategy.
- Design and implement global HEOR strategies to support pricing, reimbursement, and launch readiness (U.S. and ex-U.S.).
- Lead development of evidence frameworks for one-time gene editing therapies (lifetime value, durability, long-term uncertainty).
- Oversee primary/secondary research (HTA scans, systematic literature reviews, retrospective analyses, burden of illness, time & motion studies).
- Develop cost-effectiveness models, budget impact models (BIM), and scenario analyses for payer decision-making.
- Create/refine value narratives and dossiers (GVD, AMCP Dossier) and payer decks.
- Coordinate HTA submissions/engagement (e.g., NICE, ICER) with methodological rigor.
- Integrate evidence and economic modeling into pricing strategy, access models, and value-based agreement designs.
- Oversee RWE strategy; develop PROs and rare-disease quality-of-life instruments.
- Guide claims/data collaborations and outcomes research; lead scientific communications.
- Build/lead Field HEOR team and deliver payer-facing engagement across commercial, Medicare, and Medicaid.
- Present clinical, economic, and RWE data to Medical and Pharmacy Directors; address medical policy and utilization management.
- Train/mentor field teams; identify payer RWE collaborations to support coverage.
- Provide actionable payer insights to refine internal evidence plans and access strategy.
- Manage HEOR budget, vendors/consultants, timelines, and quality standards; ensure compliance and scientific integrity.

Qualifications/Skills:
- Strong knowledge of payer decision-making, health economics, and value demonstration.
- Direct payer engagement experience presenting clinical and economic evidence.
- Proven ability to lead RWE projects addressing payer needs.
- Expertise in payer launch deliverables; success in both field-based and in-house HEOR.
- Cross-functional partnership experience (account teams, medical affairs, clinical development).
- Excellent communication and presentation skills.
- Prior experience in rare disease, cell/gene therapy, or advanced therapeutics (preferred).
- BS/BA plus advanced degree (MPH, PhD, PharmD, MD, MS in Health Economics/Outcomes/Public Health or related).
- 10+ years in HEOR/market access/payer strategy (pharma/biotech).
- Minimum 5+ years HEOR payer-facing or field HEOR/payer medical; value-based contracting experience (preferred).
- Strong grasp of healthcare policy, reimbursement systems (Commercial, Medicare, Medicaid), and medical policy development.

Application instructions:
- Applications are accepted on a rolling basis and will be taken down once the position is filled.